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Showing 1–2 of 2 results
Advanced filters: Author: Joha Park Clear advanced filters

  • A transcription activator–like effector nuclease (TALEN)-mediated knockout approach to delete human microRNA (miRNA) genes was used to generate a library of 540 TALEN pairs for 274 miRNA loci. As a case study, single and double knockouts for two related miRNAs, miR-141 and miR-200c, revealed intriguing functional differences.

    • Young-Kook Kim
    • Gabbine Wee
    • V Narry Kim
    Research
    Nature Structural & Molecular Biology
    Volume: 20, P: 1458-1464