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Showing 1–2 of 2 results
Advanced filters: Author: Johanna M. Colijn Clear advanced filters

  • Multivariable Mendelian randomization (MR) extends the standard MR framework to consider multiple risk factors in a single model. Here, Zuber et al. propose MR-BMA, a Bayesian variable selection approach to identify the likely causal determinants of a disease from many candidate risk factors as for example high-throughput data sets.

    • Verena Zuber
    • Johanna Maria Colijn
    • Stephen Burgess
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • Here, the authors report a multi-ethnic genome wide association meta-analysis of 12 studies from the International Cataract Genetics Consortium. They find six new loci associated with age-related nuclear cataract, in addition to replicating the association at CRYAA, and suggest a strong genetic link between age-related nuclear and congenital cataracts.

    • Ekaterina Yonova-Doing
    • Wanting Zhao
    • Ching-Yu Cheng
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-8