Nature Search

Genome-guided isolation of the hyperthermophilic aerobe Fervidibacter sacchari reveals conserved polysaccharide metabolism in the Armatimonadota

Few aerobic hyperthermophilic microorganisms are known to degrade polysaccharides. Here, Nou et al. use genomic information to enrich and optical tweezers to isolate an aerobic hyperthermophilic bacterium that can grow at 65–87.5 °C using polysaccharides as sole carbon sources.

Nancy O. Nou
Jonathan K. Covington
Brian P. Hedlund
ResearchOpen Access04 Nov 2024
Nature Communications

Volume: 15, P: 1-17
Structure of porphobilinogen deaminase reveals a flexible multidomain polymerase with a single catalytic site

Gordon V. Louie
Paul D. Brownlie
Peter M. Jordan
Research03 Sept 1992
Nature

Volume: 359, P: 33-39
Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction

A national prospective study of patients requiring hospitalization for COVID-19 demonstrates global cognitive deficits at 1 year, associated with elevated brain injury markers and reduced gray matter volume.

Greta K. Wood
Brendan F. Sargent
E. Charles Leek
ResearchOpen Access23 Sept 2024
Nature Medicine

Volume: 31, P: 245-257
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

Kimberly Burns
Jonathan Clatworthy
Filippo Volpe
Research10 May 2000
Nature Cell Biology

Volume: 2, P: 346-351
Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya

Asgard archaea include the closest known archaeal relatives of eukaryotes. Here, the authors provide evidence that eukaryotic and Asgard thymidylate synthases (required for DNA synthesis) may have a bacterial origin, and additional lateral transfer of bacterial genes may have shaped the metabolism of Asgard archaea.

Jonathan Filée
Hubert F. Becker
Hannu Myllykallio
ResearchOpen Access15 Feb 2023
Nature Communications

Volume: 14, P: 1-15
Reducing sectoral hard-to-abate emissions to limit reliance on carbon dioxide removal

Moving towards net-zero emissions requires carbon dioxide removal (CDR) technologies, which bring environmental and socioeconomic risks. This study reveals that demand and technological interventions in hard-to-abate sectors help to achieve net-zero targets with less reliance on CDR.

Oreane Y. Edelenbosch
Andries F. Hof
Detlef P. van Vuuren
ResearchOpen Access07 Jun 2024
Nature Climate Change

Volume: 14, P: 715-722
The ash dieback invasion of Europe was founded by two genetically divergent individuals

The fungal pathogen Hymenoscyphus fraxineus is killing European common ash trees. Here, the authors sequence the genome of H. fraxineus and show that European populations were founded by two divergent haploid individuals introduced from Asia.

Mark McMullan
Maryam Rafiqi
Matthew D. Clark
ResearchOpen Access23 Apr 2018
Nature Ecology & Evolution

Volume: 2, P: 1000-1008
Fire-scarred fossil tree from the Late Triassic shows a pre-fire drought signal

Bruce A. Byers
Lucía DeSoto
Markus Stoffel
ResearchOpen Access18 Nov 2020
Scientific Reports

Volume: 10, P: 1-10
CO₂-enhanced melting of biotite-bearing rocks at deep-crustal pressure–temperature conditions

Jonathan W. Peterson
Robert C. Newton
Research03 Aug 1989
Nature

Volume: 340, P: 378-380
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Large-scale visualization of α-synuclein oligomers in Parkinson’s disease brain tissue

An optical detection and analysis platform quantifies aggregate density, distribution and size in fluorescently labelled post-mortem human brain tissue.

Rebecca Andrews
Bin Fu
Steven F. Lee
ResearchOpen Access01 Oct 2025
Nature Biomedical Engineering

P: 1-13
Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

Jonathan Goldberg
Hsien-bin Huang
John Kuriyan
Research31 Aug 1995
Nature

Volume: 376, P: 745-753
Pulp Nonfiction from Cellulcon '88

Jonathan Woodward
Research01 Nov 1988
Bio/Technology

Volume: 6, P: 1306
Role of methane and carbon dioxide in gold deposition

Jonathan Naden
Thomas J. Shepherd
Research14 Dec 1989
Nature

Volume: 342, P: 793-795
Sugar release and growth of biofuel crops are improved by downregulation of pectin biosynthesis

Engineered switchgrass and poplar are better feedstocks for biofuel synthesis and yield more biomass in multi-year field trials.

Ajaya K Biswal
Melani A Atmodjo
Debra Mohnen
Research12 Feb 2018
Nature Biotechnology

Volume: 36, P: 249-257
S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control

Li Jia
Celia Bonaventura
Jonathan S. Stamler
Research21 Mar 1996
Nature

Volume: 380, P: 221-226
Mature Andean forests as globally important carbon sinks and future carbon refuges

Here, the authors investigate the aboveground carbon sink efficiency of Andean forests. The study shows the high potential of these forests to serve as future carbon refuges, and urges to reduce deforestation and increase restoration.

Alvaro Duque
Miguel A. Peña
Kenneth J. Feeley
ResearchOpen Access09 Apr 2021
Nature Communications

Volume: 12, P: 1-10
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner

At the mucosal interface of the gut and microbiome immune cells play pivotal roles to regulate between commensalism, colonisation and pathogenic invasion. Here, Lo et al. show CTLA-4 expression in innate lymphoid cells is linked to mucosal homeostasis in a microbiome dependent manner.

Jonathan W. Lo
Jan-Hendrik Schroeder
Graham M. Lord
ResearchOpen Access04 Nov 2024
Nature Communications

Volume: 15, P: 1-17
A microtubule-associated protein in the mitotic spindle and the interphase nucleus

Jonathan G. Izant
James A. Weatherbee
J. Richard McIntosh
Research21 Jan 1982
Nature

Volume: 295, P: 248-250
Comprehensive molecular characterization of mitochondrial genomes in human cancers

Analysis of mitochondrial genomes (mtDNA) by using whole-genome sequencing data from 2,658 cancer samples across 38 cancer types identifies hypermutated mtDNA cases, frequent somatic nuclear transfer of mtDNA and high variability of mtDNA copy number in many cancers.

Yuan Yuan
Young Seok Ju
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature Genetics

Volume: 52, P: 342-352
Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

Tanya N. Basu
David H. Gutmann
Julian Downward
Research23 Apr 1992
Nature

Volume: 356, P: 713-715
A novel strain isolated from methane seeps in the Kattegat belongs to the planctomycetal species Novipirellula methanifontis sp. nov.

Myriel Staack
Tom Haufschild
Christian Jogler
ResearchOpen Access13 Feb 2026
Scientific Reports

Volume: 16, P: 1-11
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Analysis of whole-genome sequencing data across 2,658 tumors spanning 38 cancer types shows that chromothripsis is pervasive, with a frequency of more than 50% in several cancer types, contributing to oncogene amplification, gene inactivation and cancer genome evolution.

Isidro Cortés-Ciriano
Jake June-Koo Lee
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature Genetics

Volume: 52, P: 331-341
Genetic architecture and evolution of the S locus supergene in Primula vulgaris

The genetic model for heterostyly in Primula involves two floral morphs, pin and thrum, with reciprocal anther and stigma heights. This study reveals that the thrum morph is hemizygous and controlled by a cluster of five linked genes absent in the pin morph.

Jinhong Li
Jonathan M. Cocker
Philip M. Gilmartin
Research02 Dec 2016
Nature Plants

Volume: 2, P: 1-7
The relationship between chromosome structure and function at a human telomeric region

Jonathan Flint
Karen Thomas
Douglas R. Higgs
Research01 Mar 1997
Nature Genetics

Volume: 15, P: 252-257
Prediction of coastal sediment stability from photopigment content of mats of purple sulphur bacteria

Jonathan Grant
Giselher Gust
Research19 Nov 1987
Nature

Volume: 330, P: 244-246
Structural similarity between the p17 matrix protein of HIV-1 and interferon-γ

Stephen Matthews
Paul Barlow
Iain Campbell
Research25 Aug 1994
Nature

Volume: 370, P: 666-668
Role of RNA transcripts in replication incompatibility and copy number control in antibiotic resistance plasmid derivatives

Jonathan Rosen
Thomas Ryder
Eiichi Ohtsubo
Research30 Apr 1981
Nature

Volume: 290, P: 794-797
Black-carbon absorption enhancement in the atmosphere determined by particle mixing state

Mixing with non-black carbon can enhance the radiative effect of black-carbon aerosols. Lab and field measurements of aerosol properties reveal that the mass ratio of black to non-black carbon determines the amount of enhancement.

Dantong Liu
James Whitehead
James D. Allan
Research27 Feb 2017
Nature Geoscience

Volume: 10, P: 184-188
Language of life

Jonathan Howard
Books & Arts04 May 1989
Nature

Volume: 339, P: 26
Morphogenesis and Regulation in Spite of Continued Mitotic Inhibition in Xenopus Embryos

JONATHAN COOKE
Research02 Mar 1973
Nature

Volume: 242, P: 55-57
Emissions leakage and economic losses may undermine deforestation-linked oil crop import restrictions

Import restrictions on deforestation-linked commodities, like oil crops, could cut land-use emissions but risk emissions leakage globally and economic losses for producers. Direct forest protection may be more effective than import restrictions.

Brinda Yarlagadda
Xin Zhao
Jonathan Lamontagne
ResearchOpen Access11 Feb 2025
Nature Communications

Volume: 16, P: 1-9
The earliest record of human activity in northern Europe

Simon A. Parfitt
René W. Barendregt
Anthony J. Stuart
Research14 Dec 2005
Nature

Volume: 438, P: 1008-1012
Concerns about reported harvests in European forests

Marc Palahí
Rubén Valbuena
Gert-Jan Nabuurs
Research28 Apr 2021
Nature

Volume: 592, P: E15-E17
Author Correction: Genomic basis for RNA alterations in cancer

Claudia Calabrese
Natalie R. Davidson
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E37
Whole-genome sequencing of a sporadic primary immunodeficiency cohort

Whole-genome sequencing analysis of individuals with primary immunodeficiency identifies new candidate disease-associated genes and shows how the interplay between genetic variants can explain the variable penetrance and complexity of the disease.

James E. D. Thaventhiran
Hana Lango Allen
Kenneth G. C. Smith
Research06 May 2020
Nature

Volume: 583, P: 90-95
Author Correction: Integrative pathway enrichment analysis of multivariate omics data

Marta Paczkowska
Jonathan Barenboim
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1
Masting is uncommon in trees that depend on mutualist dispersers in the context of global climate and fertility gradients

A new method to quantify three masting components from individual tree-years has revealed that globally, masting is uncommon in tree species that depend on mutualist dispersers, with its distribution further mediated by climate and nutrient availability.

Tong Qiu
Marie-Claire Aravena
James S. Clark
Research29 Jun 2023
Nature Plants

Volume: 9, P: 1044-1056
Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon

Jordan S. Pober
Tucker Collins
Carol S. Reiss
Research20 Oct 1983
Nature

Volume: 305, P: 726-729
Whole-genome sequencing of patients with rare diseases in a national health system

Whole-genome sequencing and phenotype data sharing are introduced in a national health system to streamline diagnosis and to discover coding and non-coding variants that cause rare diseases.

Ernest Turro
William J. Astle
Willem H. Ouwehand
Research24 Jun 2020
Nature

Volume: 583, P: 96-102
The ecological benefits of more room for rivers

This Review synthesizes the ecological features and processes that arise when rivers are given room to move. Understanding these interactions will support more sustainable decisions that weigh river ecology against engineering in a rapidly changing world.

Christina L. McCabe
Christoph D. Matthaei
Jonathan D. Tonkin
Reviews21 Mar 2025
Nature Water

Volume: 3, P: 260-270
Impact of provision of abdominal aortic calcification results on fruit and vegetable intake: 12-week randomized phase 2 controlled trial

It is unclear whether providing the results of abdominal aortic calcification imaging to patients improves diet parameters. This randomized trial shows that this intervention does not lead to improvements in fruit and vegetable intake, while showing an effect on some cardiovascular disease risk factors used as secondary outcomes.

Simone Radavelli-Bagatini
Catherine P. Bondonno
Joshua R. Lewis
ResearchOpen Access14 Oct 2024
Nature Communications

Volume: 15, P: 1-11
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Ruth Loos and colleagues report results of a large genome-wide association study for body mass index. They identify 18 new loci associated with this trait, some of which map near key hypothalamic regulators of energy balance.

Elizabeth K Speliotes
Cristen J Willer
Ruth J F Loos
Research10 Oct 2010
Nature Genetics

Volume: 42, P: 937-948
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Mapping routine measles vaccination in low- and middle-income countries

Although progress in the coverage of routine measles vaccination in children in low- and middle-income countries was made during 2000–2019, many countries remain far from the goal of 80% coverage in all districts by 2019.

Alyssa N. Sbarra
Sam Rolfe
Jonathan F. Mosser
ResearchOpen Access16 Dec 2020
Nature

Volume: 589, P: 415-419
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

Jonathan D. Oliner
Jennifer A. Pietenpol
Bert Vogelstein
Research29 Apr 1993
Nature

Volume: 362, P: 857-860
Mapping genomic loci implicates genes and synaptic biology in schizophrenia

A genome-wide association study including over 76,000 individuals with schizophrenia and over 243,000 control individuals identifies common variant associations at 287 genomic loci, and further fine-mapping analyses highlight the importance of genes involved in synaptic processes.

Vassily Trubetskoy
Antonio F. Pardiñas
Jim van Os
Research08 Apr 2022
Nature

Volume: 604, P: 502-508
High aboveground carbon stock of African tropical montane forests

The aboveground carbon stock of a montane African forest network is comparable to that of a lowland African forest network and two-thirds higher than default values for these montane forests.

Aida Cuni-Sanchez
Martin J. P. Sullivan
Etienne Zibera
Research25 Aug 2021
Nature

Volume: 596, P: 536-542
A juvenile early hominin skeleton from Dikika, Ethiopia

Zeresenay Alemseged
Fred Spoor
Jonathan G. Wynn
Research21 Sept 2006
Nature

Volume: 443, P: 296-301
Functional topographic mapping of the cortical ribbon in human vision with conventional MRI scanners

Walter Schneider
Douglas C. Noll
Jonathan D. Cohen
Research09 Sept 1993
Nature

Volume: 365, P: 150-153

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