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Showing 601–645 of 645 results

Advanced filters: Author: Jonathan Chambers Clear advanced filters

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

This protocol from Feng Zhang's lab enables genome-scale knockout and transcriptional activation screening using the CRISPR-Cas9 system, as sgRNA libraries are constructed and packaged into lentiviral vectors for delivery into cells for screening.

Julia Joung
Silvana Konermann
Feng Zhang
Protocols23 Mar 2017
Nature Protocols

Volume: 12, P: 828-863
Structure and evolution of the lunar Procellarum region as revealed by GRAIL gravity data

Gravity data show a rectangular pattern of narrow linear anomalies bordering the lunar Procellarum region that are interpreted to be the frozen remnants of lava-filled rifts and underlying feeder dykes.

Jeffrey C. Andrews-Hanna
Jonathan Besserer
Maria T. Zuber
Research01 Oct 2014
Nature

Volume: 514, P: 68-71
Sequence and functional properties of Ets genes in the model organism Drosophila

Tien Hsu
Robert A Schulz
Research12 Jan 2001
Oncogene

Volume: 19, P: 6409-6416
Episodic Withdrawal Promotes Psychomotor Sensitization to Morphine

Patrick E Rothwell
Jonathan C Gewirtz
Mark J Thomas
Research01 Sept 2010
Neuropsychopharmacology

Volume: 35, P: 2579-2589
Methanethiol-dependent dimethylsulfide production in soil environments

Ornella Carrión
Jennifer Pratscher
Jonathan D Todd
ResearchOpen Access01 Aug 2017
The ISME Journal

Volume: 11, P: 2379-2390
Expression and therapeutic targeting of dopamine receptor-1 (D1R) in breast cancer

D C Borcherding
W Tong
N Ben-Jonathan
Research19 Oct 2015
Oncogene

Volume: 35, P: 3103-3113
Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium

Emily L. Dennis
Seth G. Disner
Rajendra A. Morey
Research19 Dec 2019
Molecular Psychiatry

Volume: 26, P: 4315-4330
Liquid biopsies come of age: towards implementation of circulating tumour DNA

Circulating tumour DNA (ctDNA) analysis has the potential to improve prognostication, molecular profiling and disease monitoring in patients with cancer. This Review summarizes recent advances, potential applications in cancer research and personalized oncology, and the introduction of ctDNA into clinical use.

Jonathan C. M. Wan
Charles Massie
Nitzan Rosenfeld
Reviews24 Feb 2017
Nature Reviews Cancer

Volume: 17, P: 223-238
A multiscale accuracy assessment of moisture content predictions using time-lapse electrical resistivity tomography in mine tailings

Adrien Dimech
Anne Isabelle
Jonathan Chambers
ResearchOpen Access27 Nov 2023
Scientific Reports

Volume: 13, P: 1-25
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

A large-scale GWAS provides insight on diabetes-dependent genetic effects on the glomerular filtration rate, a common metric to monitor kidney health in disease.

Thomas W. Winkler
Humaira Rasheed
Iris M. Heid
ResearchOpen Access13 Jun 2022
Communications Biology

Volume: 5, P: 1-20
D-cycloserine Deters Reacquisition of Cocaine Self-Administration by Augmenting Extinction Learning

Bríd Á Nic Dhonnchadha
Jonathan J Szalay
Kathleen M Kantak
Research09 Sept 2009
Neuropsychopharmacology

Volume: 35, P: 357-367
Distinct Profiles of Anxiety and Dysphoria during Spontaneous Withdrawal from Acute Morphine Exposure

Patrick E Rothwell
Mark J Thomas
Jonathan C Gewirtz
Research03 Jun 2009
Neuropsychopharmacology

Volume: 34, P: 2285-2295
Self-Administration of Cocaine Induces Dopamine-Independent Self-Administration of Sigma Agonists

Takato Hiranita
Maddalena Mereu
Jonathan L Katz
Research28 Nov 2012
Neuropsychopharmacology

Volume: 38, P: 605-615
Changes in nutrient stoichiometry, elemental homeostasis and growth rate of aquatic litter-associated fungi in response to inorganic nutrient supply

Vladislav Gulis
Kevin A Kuehn
Amy D Rosemond
Research21 Jul 2017
The ISME Journal

Volume: 11, P: 2729-2739
Correlating heatwaves and relative humidity with suicide (fatal intentional self-harm)

Fernando Florido Ngu
Ilan Kelman
Sonja Ayeb-Karlsson
ResearchOpen Access15 Nov 2021
Scientific Reports

Volume: 11, P: 1-9
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

A. Mesut Erzurumluoglu
Mengzhen Liu
Joanna M. M. Howson
ResearchOpen Access07 Jan 2019
Molecular Psychiatry

Volume: 25, P: 2392-2409
Drug repurposing for Alzheimer’s disease based on transcriptional profiling of human iPSC-derived cortical neurons

Gareth Williams
Ariana Gatt
Clive Ballard
ResearchOpen Access06 Sept 2019
Translational Psychiatry

Volume: 9, P: 1-10
The future of microfluidics in immune checkpoint blockade

Jonathan Briones
Wilfred Espulgar
Masato Saito
Reviews27 Oct 2020
Cancer Gene Therapy

Volume: 28, P: 895-910
Author Correction: Correlating heatwaves and relative humidity with suicide (fatal intentional self-harm)

Fernando Florido Ngu
Ilan Kelman
Sonja Ayeb-Karlsson
Amendments and CorrectionsOpen Access01 Dec 2021
Scientific Reports

Volume: 11, P: 1
The UK clinical eye research strategy: refreshing research priorities for clinical eye research in the UK

Rupert R. A. Bourne
Malik Moledina
Srilakshmi M. Sharma
ResearchOpen Access29 May 2024
Eye

Volume: 38, P: 1947-1957
Targeted therapy of human leukemia xenografts in immunodeficient zebrafish

Ranganatha R. Somasagara
Xiaoyan Huang
TinChung Leung
ResearchOpen Access11 Mar 2021
Scientific Reports

Volume: 11, P: 1-12
Regulation of motivation for food by neuromedin U in the paraventricular nucleus and the dorsal raphe nucleus

D L McCue
J M Kasper
J D Hommel
Research17 Oct 2016
International Journal of Obesity

Volume: 41, P: 120-128
Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease

Stefania Forner
Shimako Kawauchi
Kim N. Green
ResearchOpen Access15 Oct 2021
Scientific Data

Volume: 8, P: 1-16
Minimal protein-folding systems in hyperthermophilic archaea

Pongpan Laksanalamai
Timothy A. Whitehead
Frank T. Robb
Reviews01 Apr 2004
Nature Reviews Microbiology

Volume: 2, P: 315-324
The HLA-B –21 M/T dimorphism associates with disease severity in COVID-19

Benedikt Strunz
Pouria Momayyezi
Quirin Hammer
ResearchOpen Access01 Nov 2024
Genes & Immunity

Volume: 26, P: 70-74
The FLUXNET2015 dataset and the ONEFlux processing pipeline for eddy covariance data

Gilberto Pastorello
Carlo Trotta
Dario Papale
ResearchOpen Access09 Jul 2020
Scientific Data

Volume: 7, P: 1-27
Dopamine D₂-Like Receptors and Behavioral Economics of Food Reinforcement

Paul L Soto
Takato Hiranita
Jonathan L Katz
Research24 Jul 2015
Neuropsychopharmacology

Volume: 41, P: 971-978
Inhibition of autophagy prevents cadmium-induced prostate carcinogenesis

Deeksha Pal
Suman Suman
Chendil Damodaran
ResearchOpen Access06 Jun 2017
British Journal of Cancer

Volume: 117, P: 56-64
Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis

G Semenova
D S Stepanova
J Chernoff
Research22 May 2017
Oncogene

Volume: 36, P: 5421-5431
Pharmacologic synergism of ocular ketorolac and systemic caffeine citrate in rat oxygen-induced retinopathy

Jacob V. Aranda
Charles L. Cai
Kay D. Beharry
ResearchOpen Access16 May 2016
Pediatric Research

Volume: 80, P: 554-565
Lack of Specific Involvement of (+)-Naloxone and (+)-Naltrexone on the Reinforcing and Neurochemical Effects of Cocaine and Opioids

Gianluigi Tanda
Maddalena Mereu
Jonathan L Katz
Research14 Jun 2016
Neuropsychopharmacology

Volume: 41, P: 2772-2781
Increased Dopamine Receptor Activity in the Nucleus Accumbens Shell Ameliorates Anxiety during Drug Withdrawal

Anna K Radke
Jonathan C Gewirtz
Research13 Jun 2012
Neuropsychopharmacology

Volume: 37, P: 2405-2415
Progastrin a new pro-angiogenic factor in colorectal cancer

S Najib
A Kowalski-Chauvel
C Seva
Research11 Aug 2014
Oncogene

Volume: 34, P: 3120-3130
Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines

Adam FL Hurlstone
George Reid
Donald M Black
Research15 Mar 1999
Oncogene

Volume: 18, P: 1881-1890
Extensive sequencing of seven human genomes to characterize benchmark reference materials

Justin M. Zook
David Catoe
Marc Salit
ResearchOpen Access07 Jun 2016
Scientific Data

Volume: 3, P: 1-26
Cardiotrophin 1 stimulates beneficial myogenic and vascular remodeling of the heart

Mohammad Abdul-Ghani
Colin Suen
Lynn A Megeney
ResearchOpen Access08 Aug 2017
Cell Research

Volume: 27, P: 1195-1215
DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association

Lakis et al. report novel findings related to the epigenetic landscape of pancreatic neuroendocrine cancer. This relatively large cohort provides functional insights into the epigenetic wiring of pancreatic neuroendocrine tumor sub-types with the potential ability to stratify tumours of different prognosis.

Vanessa Lakis
Rita T. Lawlor
Aldo Scarpa
ResearchOpen Access03 Feb 2021
Communications Biology

Volume: 4, P: 1-11
Antiobesity effects of the β-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats

J D Roth
J L Trevaskis
D G Parkes
Research17 Jun 2008
International Journal of Obesity

Volume: 32, P: 1201-1210
A Rac–Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells

L E Arias-Romero
O Villamar-Cruz
J Chernoff
Research16 Aug 2010
Oncogene

Volume: 29, P: 5839-5849
Metabolomic and exposomic biomarkers of risk of future neurodevelopmental delay in human milk

Kefeng Li
Kerri Bertrand
Christina Chambers
ResearchOpen Access15 Sept 2022
Pediatric Research

Volume: 93, P: 1710-1720
Assessment of long-term neurodevelopmental outcome following trials of medicinal products in newborn infants

Neil Marlow
Lex W. Doyle
Mark A. Turner
ReviewsOpen Access09 Aug 2019
Pediatric Research

Volume: 86, P: 567-572
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Jason Flannick
Christian Fuchsberger
Mark I. McCarthy
ResearchOpen Access19 Dec 2017
Scientific Data

Volume: 4, P: 1-22
Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Jason Flannick
Christian Fuchsberger
Mark I. McCarthy
Amendments and CorrectionsOpen Access23 Jan 2018
Scientific Data

Volume: 5, P: 1-2
Analytical imaging studies of the migration of degraded orpiment, realgar, and emerald green pigments in historic paintings and related conservation issues

Katrien Keune
Jennifer Mass
Florian Meirer
articlesOpen Access21 Apr 2016
Heritage Science

Volume: 4, P: 1-14
The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells

F F Blanco
M Jimbo
J R Brody
Research21 Sept 2015
Oncogene

Volume: 35, P: 2529-2541

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