Gene expression fluctuates in concert with the day/night cycle, and this results in differential behaviours throughout the day. These changes in expression have been studied at the transcriptional and post-translational levels. Here, another type of circadian-influenced regulation that occurs at the post-transcriptional level is defined. The twenty-four (TYF) protein associates with the mRNA of the clock protein PER, enhancing its translation.
- Chunghun Lim
- Jongbin Lee
- Joonho Choe