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Showing 1–5 of 5 results
Advanced filters: Author: Jordan Spatz Clear advanced filters

  • A major challenge in coronavirus vaccination and treatment is to counteract rapid viral evolution and mutations. Here the authors show that CRISPR-Cas13d can be used as a broad-spectrum antiviral to inhibit human coronaviruses, including new SARS-CoV-2 variants, combined with small molecule drugs for an enhanced antiviral effect in human primary cells.

    • Leiping Zeng
    • Yanxia Liu
    • Lei S. Qi
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • Nanoreactors that isolate chemical precursors within a confined space are promising tools for synthesizing nanoparticles. This Review unifies the many classes of solution-based and substrate-confined nanoreactors, evaluating their current synthetic capabilities and their potential for solving future challenges in nanoparticle synthesis.

    • Jordan H. Swisher
    • Liban Jibril
    • Chad A. Mirkin
    Reviews
    Nature Reviews Materials
    Volume: 7, P: 428-448

  • Algorithms that account for and overcome the intrinsic pixel-dependent readout noise from scientific complementary metal-oxide semiconductor (sCMOS) cameras prevent localization artifacts and avoid substantial compromises in localization uncertainty in single-molecule imaging. When combined with multi-emitter fitting, sCMOS cameras allow video-rate single-molecule switching nanoscopy.

    • Fang Huang
    • Tobias M P Hartwich
    • Joerg Bewersdorf
    Research
    Nature Methods
    Volume: 10, P: 653-658