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Showing 1–4 of 4 results
Advanced filters: Author: Jordane Depagne Clear advanced filters

  • Rad51/RecA filament formation is key to homologous recombination. Here the authors combine structural studies with analyses in yeast to show that an 85-residue segment of Rad52 acts as a chaperone that binds Rad51 monomers promoting nucleation on ssDNA and counteracting the Srs2 translocase.

    • Emilie Ma
    • Fadma Lakhal
    • Eric Coïc
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18

  • Different proteins localised at telomeres ensure chromosome end stability to prevent double strand-end break recognition. Here the authors provide new insight into how in S. cerevisiae the interaction between Rif2 and Rad50 inhibits MRX functions at telomeres.

    • Florian Roisné-Hamelin
    • Sabrina Pobiega
    • Stéphane Marcand
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16

  • The ComFC protein is essential for natural transformation, a process that plays a major role in the spread of antibiotic resistance genes. Here the authors show that ComFC is a membrane-associated protein that participates in the transport of DNA through the cell membrane and the handling of the single-stranded DNA once delivered into the cytoplasm.

    • Prashant P. Damke
    • Louisa Celma
    • J. Pablo Radicella
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13