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Advanced filters: Author: Joris van Arensbergen Clear advanced filters

High-throughput identification of human SNPs affecting regulatory element activity

Application of SuRE reporter technology to survey the effect of 5.9 million SNPs in the human genome on enhancer and promoter activity identifies over 30,000 SNPs that alter the activity of putative regulatory elements.

Joris van Arensbergen
Ludo Pagie
Bas van Steensel
Research28 Jun 2019
Nature Genetics

Volume: 51, P: 1160-1169
Genome-wide mapping of autonomous promoter activity in human cells

The intrinsic strength of promoter sequences in driving transcription is measured across the human genome.

Joris van Arensbergen
Vincent D FitzPatrick
Bas van Steensel
Research26 Dec 2016
Nature Biotechnology

Volume: 35, P: 145-153

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High-throughput identification of human SNPs affecting regulatory element activity

Genome-wide mapping of autonomous promoter activity in human cells

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