Gringhuis, Geijtenbeek and colleagues show that the RNA helicase DDX3 binds abortive HIV-1 RNA and induces type I interferon in dendritic cells, a process that is inhibited by the HIV-1-induced activation of kinase PLK1.
- Sonja I Gringhuis
- Nina Hertoghs
- Teunis B H Geijtenbeek
