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Showing 1–3 of 3 results
Advanced filters: Author: Joscha Weiss Clear advanced filters

  • Using cryo-electron microscopy, the authors determine the structure of cGAS bound to nucleosomes and present evidence for the mechanism by which nucleosome binding to cGAS prevents cGAS dimerization and its binding to free double-stranded DNA.

    • Ganesh R. Pathare
    • Alexiane Decout
    • Andrea Ablasser
    Research
    Nature
    Volume: 587, P: 668-672

  • Cryo-EM structures and analysis provide insight into the mechanisms by which basic helix–loop–helix transcription factors access E-box DNA sequences that are embedded within nucleosomes, and cooperate with other transcription factors.

    • Alicia K. Michael
    • Lisa Stoos
    • Nicolas H. Thomä
    ResearchOpen Access
    Nature
    Volume: 619, P: 385-393