Actinoporins are water-soluble pore-forming toxins that self-assemble in the membranes of target cells. Here, the authors provide insight into the mechanism of membrane pore formation by solving the structures of several states of the hemolytic protein fragaceatoxin C, including the fully assembled pore.
- Koji Tanaka
- Jose M.M. Caaveiro
- Kouhei Tsumoto
