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Showing 1–14 of 14 results
Advanced filters: Author: Jose U. Scher Clear advanced filters

  • This Review explores the complex relationship between obesity and psoriatic disease. The authors highlight the underlying mechanisms that drive this association and propose a comprehensive approach to managing obesity in individuals with psoriatic disease to improve overall disease management and therapeutic response.

    • Rebecca H. Haberman
    • Alexis Ogdie
    • Lihi Eder
    Reviews
    Nature Reviews Rheumatology
    P: 1-14

  • In this article, the authors critically appraise the current model of opinion-based academia–industry interactions, and advocate for a realignment towards partnerships that foster innovation and knowledge.

    • Jose U. Scher
    • Georg Schett
    Reviews
    Nature Reviews Rheumatology
    Volume: 17, P: 119-124

  • The microbes that inhabit our bodies play an important part in regulating the homeostasis of the immune system—disequilibrium in this symbiotic relationship can lead to development of disease. In this Review, the authors present an overview of the historical evidence implicating microbes in the development of rheumatoid arthritis (RA), and describe how the use of DNA sequencing techniques and germ–free animal models of disease are elucidating the role of host–microbial interactions in the pathogenesis of RA.

    • Jose U. Scher
    • Steven B. Abramson
    Reviews
    Nature Reviews Rheumatology
    Volume: 7, P: 569-578

  • Environmental exposures shape patterns of selection for mutations in clonal hematopoiesis. Cancer therapies promote the growth of clones with mutations that are strongly enriched in treatment-related myeloid neoplasms.

    • Kelly L. Bolton
    • Ryan N. Ptashkin
    • Elli Papaemmanuil
    Research
    Nature Genetics
    Volume: 52, P: 1219-1226

  • In this Consensus Statement, an expert panel from the Psoriasis and Psoriatic Arthritis Clinics Multicenter Advancement Network (PPACMAN) recommends terminology for defining specific subgroups of individuals during the preclinical and early clinical phases of psoriatic arthritis to be used in research studies.

    • Lourdes M. Perez-Chada
    • Rebecca H. Haberman
    • Jose U. Scher
    ReviewsOpen Access
    Nature Reviews Rheumatology
    Volume: 17, P: 238-243

  • This Review provides an overview of new discoveries that are changing our understanding of the complex role of the human gut microbiota and its metabolites in health and disease, including their effects on rheumatic diseases. Factors that modulate the microbiota, such as diet and probiotics, and advances in pharmacomicrobiomics are also discussed.

    • Shahla Abdollahi-Roodsaz
    • Steven B. Abramson
    • Jose U. Scher
    Reviews
    Nature Reviews Rheumatology
    Volume: 12, P: 446-455

  • Psoriatic arthritis (PsA) is a chronic immune-mediated form of arthritis that occurs in some patients with psoriasis. This Primer reviews the epidemiology and pathophysiology of PsA and highlights the challenges in diagnosis and advances in treatment. In addition, the authors discuss the quality of life of patients and outstanding questions in the field.

    • Oliver FitzGerald
    • Alexis Ogdie
    • Philip J. Mease
    Reviews
    Nature Reviews Disease Primers
    Volume: 7, P: 1-17

  • In this Review, the authors discuss a comprehensive mechanistic concept of psoriatic arthritis, including discussion of the genetic, biomechanical, metabolic and microbial factors that contribute to the development of the disease as well as its manifestations and consequences.

    • Georg Schett
    • Proton Rahman
    • Jose U. Scher
    Reviews
    Nature Reviews Rheumatology
    Volume: 18, P: 311-325