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Advanced filters: Author: Josef Redolfi Clear advanced filters

DamC reveals principles of chromatin folding in vivo without crosslinking and ligation

A modified version of DamID allows measurement of chromosomal interactions without crosslinking and ligation, and provides validation for the existence of TADs in mESCs.

Josef Redolfi
Yinxiu Zhan
Luca Giorgetti
Research27 May 2019
Nature Structural & Molecular Biology

Volume: 26, P: 471-480
Nonlinear control of transcription through enhancer–promoter interactions

The transcriptional effect of an enhancer depends on its contact probabilities with the promoter through a nonlinear relationship, and enhancer strength determines absolute transcription levels as well as the sensitivity of a promoter to CTCF-mediated transcriptional insulation.

Jessica Zuin
Gregory Roth
Luca Giorgetti
ResearchOpen Access13 Apr 2022
Nature

Volume: 604, P: 571-577
Electron tomography of mouse LINC complexes at meiotic telomere attachment sites with and without microtubules

Marie-Christin Spindler et al. present quantitative information on telomere attachment to LINC complexes during meiosis using electron microscope tomography. They show that an average of 76 LINC complexes is needed to move a telomere attachment site.

Marie-Christin Spindler
Josef Redolfi
Ricardo Benavente
ResearchOpen Access14 Oct 2019
Communications Biology

Volume: 2, P: 1-11
MISTIC-fusion proteins as antigens for high quality membrane protein antibodies

Natalia Silva Alves
Susanne Adina Astrinidis
Wolfram Antonin
ResearchOpen Access02 Feb 2017
Scientific Reports

Volume: 7, P: 1-12