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Showing 1–9 of 9 results
Advanced filters: Author: Josemir W. Sander Clear advanced filters

  • A recent longitudinal study indicates that the incidence of new-onset epilepsy has remained stable in children and young adults but has increased in elderly individuals over the past 40 years. Rather than signalling a failure to prevent epilepsy, however, this phenomenon might be attributable to the comorbidities of epilepsy.

    • Josemir W. Sander
    • Mark R. Keezer
    News & Views
    Nature Reviews Neurology
    Volume: 12, P: 254-256

  • Sudden unexpected death in epilepsy most frequently occurs in people with chronic epilepsy, and seems to be a seizure-related event. In this article, Surges et al. review the incidence of sudden unexpected death in epilepsy and the risk factors associated with this condition, before exploring the pathological mechanisms related to chronic epilepsy that could lead to sudden death.

    • Rainer Surges
    • Roland D. Thijs
    • Josemir W. Sander
    Reviews
    Nature Reviews Neurology
    Volume: 5, P: 492-504

  • Familial cortical myoclonic tremor (FAME) has so far been mapped to regions on chromosome 2, 3, 5 and 8 and pentameric repeat expansions in SAMD12 were identified as cause of FAME1. Here, Corbett et al. identify ATTTT/ATTTC repeat expansions in intron 1 of STARD7 in individuals with FAME2.”

    • Mark A. Corbett
    • Thessa Kroes
    • Jozef Gecz
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10

  • Epilepsies are common brain disorders and are classified based on clinical phenotyping, imaging and genetics. Here, the authors perform genome-wide association studies for 3 broad and 7 subtypes of epilepsy and identify 16 loci - 11 novel - that are further annotated by eQTL and partitioned heritability analyses.

    • Bassel Abou-Khalil
    • Pauls Auce
    • Fritz Zimprich
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-15

  • Zoonotic and vector-borne parasites are important preventable risk factors for epilepsy. The authors explore the pathophysiological basis of the link between parasitic infections and epilepsy and consider preventive and therapeutic approaches to reduce the epilepsy burden associated with parasitic disorders.

    • Gagandeep Singh
    • Samuel A. Angwafor
    • Josemir W. Sander
    Reviews
    Nature Reviews Neurology
    Volume: 16, P: 333-345

  • Headaches and epilepsy frequently co-exist in the same individual, but the pathophysiological mechanisms underlying this relationship are not yet clear. Here, the authors discuss the epidemiological and pathophysiological links between epilepsy and headache, and apply this knowledge to the clinical management of the two disorders.

    • Prisca R. Bauer
    • Else A. Tolner
    • Josemir W. Sander
    Reviews
    Nature Reviews Neurology
    Volume: 17, P: 529-544