Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–13 of 13 results
Advanced filters: Author: Joyce Van Eck Clear advanced filters

  • A study developed genomic resources and efficient transformation in the orphan crop groundcherry, and managed to improve productivity traits by editing the orthologues of tomato domestication and improvement genes using CRISPR–Cas9.

    • Zachary H. Lemmon
    • Nathan T. Reem
    • Zachary B. Lippman
    Research
    Nature Plants
    Volume: 4, P: 766-770

  • Zachary Lippman and colleagues report mutations in the tomato ortholog of CLV1 and a gene encoding a hydroxyproline O-arabinosyltransferase enzyme that modifies CLV3, both of which cause fasciated flowers and fruits owing to increased meristem size. They also find that a natural mutation in CLV3 was a major target of selection during tomato domestication.

    • Cao Xu
    • Katie L Liberatore
    • Zachary B Lippman
    Research
    Nature Genetics
    Volume: 47, P: 784-792

  • Gene duplication and subsequent paralogue diversification shape phenotypes. This study shows how paralogues controlling stem cell proliferation evolve over short time scales and provides an evo-devo perspective for trait engineering in crop design.

    • Choon-Tak Kwon
    • Lingli Tang
    • Zachary B. Lippman
    Research
    Nature Plants
    Volume: 8, P: 346-355

  • Tomato breeding with a desirable MADS-box mutation to improve harvesting can often result in unwanted traits due to negative epistatis with cryptic mutations. A dosage mechanism involving a duplication of a second gene to overcoming the negative epistasis is dissected, enabling the design of gene editing strategies to predictably improve harvesting.

    • Sebastian Soyk
    • Zachary H. Lemmon
    • Zachary B. Lippman
    Research
    Nature Plants
    Volume: 5, P: 471-479

  • This paper reports the genome sequence of domesticated tomato, a major crop plant, and a draft sequence for its closest wild relative; comparative genomics reveal very little divergence between the two genomes but some important differences with the potato genome, another important food crop in the genus Solanum.

    • Shusei Sato
    • Satoshi Tabata
    • René M. Klein Lankhorst
    ResearchOpen Access
    Nature
    Volume: 485, P: 635-641

  • Zachary Lippman, José Jiménez-Gómez and colleagues show that cultivated tomatoes have lost day-length-sensitive flowering, compared to their wild relatives, as a result of cis-regulatory variation affecting expression of SP5G, a paralog of the florigen gene SFT. They engineered SP5G loss-of-function mutant plants, resulting in rapid flowering and early yield.

    • Sebastian Soyk
    • Niels A Müller
    • Zachary B Lippman
    Research
    Nature Genetics
    Volume: 49, P: 162-168

  • Gene editing may shape the future of foods, providing a sustainable solution for obtaining food products of high yield and nutritional value. This Review discusses the capabilities and applications of CRISPR–Cas-based gene editing of food, highlighting the technologies for improving the nutritional value of crops and animal and probiotic food products, and summarizing regulatory policies worldwide.

    • Aytug Tuncel
    • Changtian Pan
    • Yiping Qi
    Reviews
    Nature Reviews Bioengineering
    Volume: 1, P: 799-816