Concise and enantioenriched synthesis of chiral carbocyclic and heterocyclic spirane scaffolds is a significant objective in both academic and industrial fields. Here, the authors report the kinetic resolution of racemic spirocyclic 1,3-diketones and their analogues via catalytic asymmetric hydrogenation with the SPA-PNN ligands.
- Yong-Yao Li
- Ka Lu
- Yong-Qiang Tu
