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Advanced filters: Author: Juannan Zhou Clear advanced filters

  • High-throughput combinatorial mutagenesis assays are useful to screen the function of many different sequences but they are not exhaustive. Here, Zhou and McCandlish develop a method to impute such missing genotype-phenotype data based on inferring the least epistatic sequence-function relationship.

    • Juannan Zhou
    • David M. McCandlish
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14