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Showing 51–91 of 91 results

Advanced filters: Author: Judith C. Chow Clear advanced filters

Relationship between indoor, outdoor, and personal fine particle concentrations for individuals with COPD and predictors of indoor-outdoor ratio in Mexico city

Marlene Cortez-Lugo
Hortensia Moreno-Macias
Isabelle Romieu
Research04 Apr 2007
Journal of Exposure Science & Environmental Epidemiology

Volume: 18, P: 109-115
β-Hydroxybutyrate suppresses colorectal cancer

The growth of colorectal cancer is reduced by ketogenic diet consumption, the properties of which are mediated by the ketone body β-hydroxybutyrate.

Oxana Dmitrieva-Posocco
Andrea C. Wong
Maayan Levy
Research27 Apr 2022
Nature

Volume: 605, P: 160-165
Detectable clonal mosaicism and its relationship to aging and cancer

Luis Pérez-Jurado, Stephen Chanock and colleagues detect clonal chromosomal abnormalities in peripheral blood or buccal samples from individuals in the general population. They show that the frequency of such events increases with age and is associated with elevated risk of developing subsequent hematological cancers.

Kevin B Jacobs
Meredith Yeager
Stephen J Chanock
Research06 May 2012
Nature Genetics

Volume: 44, P: 651-658
Systemic induction of senescence in young mice after single heterochronic blood exchange

A single transfer of blood from old male mice is shown to induce cellular and tissue senescence in young animals, unless old mice are treated with senolytic drugs before blood exchange.

Ok Hee Jeon
Melod Mehdipour
Irina M. Conboy
Research28 Jul 2022
Nature Metabolism

Volume: 4, P: 995-1006
Cotranslational signal-independent SRP preloading during membrane targeting

The signal recognition particle (SRP) preferentially binds peptides destined for secretion before peptide-targeting signals are translated through recognition of elements in their mRNA, including non-coding sequences.

Justin W. Chartron
Katherine C. L. Hunt
Judith Frydman
Research03 Aug 2016
Nature

Volume: 536, P: 224-228
A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

Akkermansia muciniphila, a member of the gut microbiome, has been shown to improve metabolism in mice. Here it is reported that its pasteurization further improves this effect, and that one of its membrane proteins by itself has a similar benefit.

Hubert Plovier
Amandine Everard
Patrice D Cani
Research28 Nov 2016
Nature Medicine

Volume: 23, P: 107-113
Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders

The gut microbiota has been linked to non-alcoholic fatty liver disease (NAFLD), but metabolic confounding factors, such as obesity and diabetes, complicate analysis. This Review provides a broad insight into microbiome signatures for human NAFLD and explores issues with disentangling them from underlying metabolic disorders.

Judith Aron-Wisnewsky
Chloé Vigliotti
Karine Clément
Reviews09 Mar 2020
Nature Reviews Gastroenterology & Hepatology

Volume: 17, P: 279-297
Correction: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome

Kerstin Howe
Matthew D. Clark
Derek L. Stemple
Amendments and Corrections11 Dec 2013
Nature

Volume: 505, P: 248
Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery

T. G. Mastenbroek
M. F. A. Karel
J. M. E. M. Cosemans
ResearchOpen Access09 Nov 2020
Scientific Reports

Volume: 10, P: 1-14
Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Several studies show that APOE-ε4 coding variants are associated with Alzheimer’s disease (AD) risk. Here, Zhou et al. perform fine-mapping of the APOE region and find AD risk haplotypes with non-coding variants in the PVRL2 and APOC1 regions that are associated with relevant endophenotypes.

Xiaopu Zhou
Yu Chen
Nancy Y. Ip
ResearchOpen Access25 Jul 2019
Nature Communications

Volume: 10, P: 1-16
AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer

Daniela Welcker
Manaswita Jain
Katja Höpker
Research11 Jan 2018
Oncogene

Volume: 37, P: 1503-1518
Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota

Here, the authors designed a lipopeptide, Pam-3, based on an eight-amino acid carboxyl-terminal fragment of human β-defensin 1 with prominent antimicrobial activity against multidrug-resistant ESKAPE pathogens and antibiofilm properties. They show in mouse models, that Pam-3 selectively reduced acute intestinal Salmonella and established Citrobacter infections, without compromising the core microbiota.

Louis Koeninger
Lisa Osbelt
Jan Wehkamp
ResearchOpen Access08 Jan 2021
Communications Biology

Volume: 4, P: 1-11
A study of soluble protein and sulfhydryl levels in the rat liver during rapid normal and premalignant growth

Mary F Argus
Janis A Walder
J C Arcos
Research01 Jun 1968
British Journal of Cancer

Volume: 22, P: 330-341
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

Campisi and colleagues show that the MTOR inhibitor rapamycin blocks the senescence-associated secretory phenotype (SASP) by inhibiting translation of IL1A, which prevents senescent fibroblasts from promoting tumour growth.

Remi-Martin Laberge
Yu Sun
Judith Campisi
Research06 Jul 2015
Nature Cell Biology

Volume: 17, P: 1049-1061
X-linked creatine transporter deficiency results in prolonged QTc and increased sudden death risk in humans and disease model

Mark D. Levin
Simona Bianconi
Fady Hannah-Shmouni
Research28 May 2021
Genetics in Medicine

Volume: 23, P: 1864-1872
Development of outbred CD1 mouse colonies with distinct standardized gut microbiota profiles for use in complex microbiota targeted studies

Marcia L. Hart
Aaron C. Ericsson
Craig L. Franklin
ResearchOpen Access04 Jul 2018
Scientific Reports

Volume: 8, P: 1-11
1639 EFFECT OF THE NEPHROTIC SYNDROME ON THE CONCENTRATION OF SERUM COMPLEMENT COMPONENTS

C Frederic Strife
Elizabeth C Jackson
Clark D West
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 384
Stress native T1 and native T2 mapping compared to myocardial perfusion reserve in long-term follow-up of severe Covid-19

Jannike Nickander
Rebecka Steffen Johansson
Henrik Engblom
ResearchOpen Access13 Mar 2023
Scientific Reports

Volume: 13, P: 1-9
Knockout serotonin transporter in rats moderates outcome and stimulus generalization

Chao Ciu-Gwok Guo
Tao He
Judith Homberg
ResearchOpen Access07 Jan 2021
Translational Psychiatry

Volume: 11, P: 1-12
The zebrafish reference genome sequence and its relationship to the human genome

A high-quality sequence assembly of the zebrafish genome reveals the largest gene set of any vertebrate and provides information on key genomic features, and comparison to the human reference genome shows that approximately 70% of human protein-coding genes have at least one clear zebrafish orthologue.

Kerstin Howe
Matthew D. Clark
Derek L. Stemple
ResearchOpen Access17 Apr 2013
Nature

Volume: 496, P: 498-503
Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice

Guilielmus H. J. M. Ellenbroek
Judith J. de Haan
Saskia C. A. de Jager
ResearchOpen Access21 Dec 2017
Scientific Reports

Volume: 7, P: 1-13
Chronic inhibition of GABA synthesis in the infralimbic cortex facilitates conditioned safety memory and reduces contextual fear

Judith C. Kreutzmann
Markus Fendt
ResearchOpen Access24 Apr 2020
Translational Psychiatry

Volume: 10, P: 1-10
Immunogenicity and protective efficacy of RSV G central conserved domain vaccine with a prefusion nanoparticle

Jennifer N. Rainho-Tomko
Vincent Pavot
Gary J. Nabel
ResearchOpen Access30 Jun 2022
npj Vaccines

Volume: 7, P: 1-9
A critical bioenergetic switch is regulated by IGF2 during murine cartilage development

Murine chondrocyte hypertrophy was found to require IGF2-regulated bioenergetic reprogramming, in which glucose utilization shifts from glycolysis to oxidative phosphorylation as chondrocytes mature.

Judith M. Hollander
Lingyun Li
Li Zeng
ResearchOpen Access11 Nov 2022
Communications Biology

Volume: 5, P: 1-13
Inducible knockout of Clec16a in mice results in sensory neurodegeneration

Heather S. Hain
Rahul Pandey
Hakon Hakonarson
ResearchOpen Access29 Apr 2021
Scientific Reports

Volume: 11, P: 1-14
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

A Hinney
M Kesselmeier
J Hebebrand
Research17 May 2016
Molecular Psychiatry

Volume: 22, P: 192-201
Biallelic variants in HPDL, encoding 4-hydroxyphenylpyruvate dioxygenase-like protein, lead to an infantile neurodegenerative condition

Shereen G. Ghosh
Sangmoon Lee
Joseph G. Gleeson
Research14 Nov 2020
Genetics in Medicine

Volume: 23, P: 524-533
The soluble guanylate cyclase stimulator riociguat reduces fibrogenesis and portal pressure in cirrhotic rats

Philipp Schwabl
Ksenia Brusilovskaya
Thomas Reiberger
ResearchOpen Access19 Jun 2018
Scientific Reports

Volume: 8, P: 1-13
Hemodynamics of dexamethasone-induced hypertension in the rat

Sharon Leng Hong Ong
Yi Zhang
Judith Ann Whitworth
Research31 Jul 2009
Hypertension Research

Volume: 32, P: 889-894
Small litter size impairs spatial memory and increases anxiety- like behavior in a strain-dependent manner in male mice

Ali-Akbar Salari
Hanieh Samadi
Morteza Kosari-Nasab
ResearchOpen Access26 Jul 2018
Scientific Reports

Volume: 8, P: 1-12
Beyond the brain-Peripheral kisspeptin signaling is essential for promoting endometrial gland development and function

Silvia León
Daniela Fernandois
Andy V. Babwah
ResearchOpen Access01 Jul 2016
Scientific Reports

Volume: 6, P: 1-17
Dog-ownership and paediatric neurodevelopmental disorders; ‘pawsitive’ impact: a systematic review

Tiarnán Ó Conaill
Ailbhe Whitty
Eleanor J Molloy
ReviewsOpen Access30 Jul 2025
Pediatric Research

P: 1-11
Decreasing concentrations of carbonaceous aerosols in China from 2003 to 2013

Yan Cheng
Judith C. Chow
Junji Cao
ResearchOpen Access05 Mar 2021
Scientific Reports

Volume: 11, P: 1-10
Inactivation of TGF-β signaling in hepatocytes results in an increased proliferative response after partial hepatectomy

Judith Romero-Gallo
Elif G Sozmen
William M Grady
Research07 Feb 2005
Oncogene

Volume: 24, P: 3028-3041
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Zhou et al. utilise deep learning to improve polygenic risk analysis for Alzheimer’s disease. Their computational approach outperforms existing statistical methods and helps to identify potential biological mechanisms of Alzheimer’s disease risk.

Xiaopu Zhou
Yu Chen
Nancy Y. Ip
ResearchOpen Access06 Apr 2023
Communications Medicine

Volume: 3, P: 1-20
Effect of Helicobacter pylori eradication on gastric carcinogenesis

Judith Romero-Gallo
Elizabeth J Harris
Richard M Peek Jr
Research07 Jan 2008
Laboratory Investigation

Volume: 88, P: 328-336
A novel system to generate WTC dust particles for inhalation exposures

Joshua M Vaughan
Brittany J Garrett
Mitchell D Cohen
Research13 Nov 2013
Journal of Exposure Science & Environmental Epidemiology

Volume: 24, P: 105-112
Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy

Marieke A de Graaff
Marije A J de Rooij
Judith V M G Bovée
ResearchOpen Access03 May 2016
British Journal of Cancer

Volume: 114, P: 1219-1226
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Edward J Saunders
Tokhir Dadaev
Zsofia Kote-Jarai
ResearchOpen Access10 Mar 2016
British Journal of Cancer

Volume: 114, P: 945-952
Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition

Jana Lubec
Predrag Kalaba
Gert Lubec
News09 Jul 2021
Molecular Psychiatry

Volume: 26, P: 7076-7090
NY-ESO-1 (CTAG1B) expression in mesenchymal tumors

Makoto Endo
Marieke A de Graaff
Torsten O Nielsen
Research21 Nov 2014
Modern Pathology

Volume: 28, P: 587-595

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