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Maveropepimut-S, pembrolizumab and low dose cyclophosphamide in metastatic ovarian cancer: phase 1/2 PESCO trial

Epithelial ovarian cancer (EOC) frequently relapses with rising chemoresistance. This phase 1/2 trial evaluates MVP-S vaccination plus pembrolizumab and cyclophosphamide in recurrent EOC, assessing safety, clinical efficacy outcomes, and MVP-S-specific immunity.

Ana C. Veneziani
Stephanie Lheureux
Amit M. Oza
ResearchOpen Access14 May 2026
Nature Communications

P: 1-12

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Maveropepimut-S, pembrolizumab and low dose cyclophosphamide in metastatic ovarian cancer: phase 1/2 PESCO trial

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