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Advanced filters: Author: Jule Samson Clear advanced filters

  • The lysine-specific histone demethylase 1 A (LSD1) can regulate cytotoxic CD8 T cell (CTL) responses and anti-tumor immunity. Here the authors show that ex vivo epigenetic reprogramming with a LSD1 inhibitor enhances cell persistence and anti-tumor activity of adoptively transferred CD8 T cells in preclinical tumor models.

    • Isabella Pallavicini
    • Teresa Maria Frasconi
    • Teresa Manzo
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15