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Showing 1–3 of 3 results
Advanced filters: Author: Julia Bleier Clear advanced filters

  • Combined single-molecule spectroscopy, hydrogen–deuterium exchange and molecular dynamics approaches reveal that agonist activation of metabotropic glutamate receptors entails population of several intermediary states before G protein coupling.

    • Naomi R. Latorraca
    • Sam Sabaat
    • Ehud Y. Isacoff
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 21, P: 1433-1443

  • Super-resolution quantal imaging relates transmission at excitatory synapses to presynaptic molecular composition. The authors find that evoked transmission varies greatly between synapses and is uncorrelated and physically separate from spontaneous transmission, and identify responsible presynaptic proteins.

    • Zachary L. Newman
    • Dariya Bakshinskaya
    • Ehud Y. Isacoff
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18