Nature Search

High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure

Daniel Scheiber
Tomas Jelenik
Julia Szendroedi
ResearchOpen Access14 Feb 2019
Experimental & Molecular Medicine

Volume: 51, P: 1-10
Associations between cognitive performance and Mediterranean dietary pattern in patients with type 1 or type 2 diabetes mellitus

Theresa Kössler
Katharina S. Weber
D. Ziegler
ResearchOpen Access01 Apr 2020
Nutrition & Diabetes

Volume: 10, P: 1-6
Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic ¹³C magnetic resonance spectroscopy

There are currently a paucity of approaches for the direct in vivo assessment of rates of hepatic mitochondrial oxidation and anaplerotic flux in humans. With this in mind, Douglas Befroy and colleagues have developed a new ¹³C-labeling strategy that they use in combination with ¹³C magnetic resonance spectroscopy, which should prove useful in determining the potential role of changes in hepatic mitochondrial fat oxidation in diseases such as nonalcoholic fatty liver disease and type 2 diabetes.

Douglas E Befroy
Rachel J Perry
Gerald I Shulman
Research08 Dec 2013
Nature Medicine

Volume: 20, P: 98-102
Dynamic changes of muscle insulin sensitivity after metabolic surgery

Surgical weight-loss interventions improve insulin sensitivity via incompletely understood mechanisms. Here the authors assess skeletal muscle epigenetic changes in individuals with obesity following metabolic surgery and compare them with data from individuals without obesity.

Sofiya Gancheva
Meriem Ouni
Michael Roden
ResearchOpen Access13 Sept 2019
Nature Communications

Volume: 10, P: 1-13
The role of mitochondria in insulin resistance and type 2 diabetes mellitus

This Review discusses the association between mitochondrial function and insulin sensitivity in various tissues, such as skeletal muscle, liver and heart, with a main focus on studies in humans, and addresses the effects of therapeutic strategies that affect mitochondrial function and insulin sensitivity.

Julia Szendroedi
Esther Phielix
Michael Roden
Reviews13 Sept 2011
Nature Reviews Endocrinology

Volume: 8, P: 92-103
Author Correction: Dynamic changes of muscle insulin sensitivity after metabolic surgery

Sofiya Gancheva
Meriem Ouni
Michael Roden
Amendments and CorrectionsOpen Access10 Jun 2022
Nature Communications

Volume: 13, P: 1-12
Cohort profile of the Heidelberg study on diabetes and complications HEIST-DiC

Elisabeth Kliemank
Ekaterina von Rauchhaupt
Alba Sulaj
ResearchOpen Access12 Aug 2025
Scientific Reports

Volume: 15, P: 1-21
Reduced expression of stearoyl-CoA desaturase-1, but not free fatty acid receptor 2 or 4 in subcutaneous adipose tissue of patients with newly diagnosed type 2 diabetes mellitus

Kálmán Bódis
Sabine Kahl
M. Roden
ResearchOpen Access07 Sept 2018
Nutrition & Diabetes

Volume: 8, P: 1-9
Lower serum extracellular superoxide dismutase levels are associated with polyneuropathy in recent-onset diabetes

Alexander Strom
Kirti Kaul
Dan Ziegler
ResearchOpen Access17 Nov 2017
Experimental & Molecular Medicine

Volume: 49, P: e394
Metabolic surgery-induced changes of the growth hormone system relate to improved adipose tissue function

Sofiya Gancheva
Sabine Kahl
Michael Roden
ResearchOpen Access23 Mar 2023
International Journal of Obesity

Volume: 47, P: 505-511
Effects of Olanzapine and Ziprasidone on Glucose Tolerance in Healthy Volunteers

Julia Sacher
Nilufar Mossaheb
Siegfried Kasper
Research22 Aug 2007
Neuropsychopharmacology

Volume: 33, P: 1633-1641

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