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Showing 1–2 of 2 results
Advanced filters: Author: Julie Coudenys Clear advanced filters

  • PEGylated liposomal accumulation in inflamed regions has mainly been attributed to the enhanced permeation and retention effect. An arthritis model that chemotactically attracted myeloid cells shows that monocytes and neutrophils play an essential role in liposome delivery towards inflamed joints.

    • Joke Deprez
    • Rein Verbeke
    • Ine Lentacker
    Research
    Nature Nanotechnology
    Volume: 18, P: 1341-1350

  • The role of innate T cell subsets in the pathogenesis of spondyloarthritis (SpA) is not well understood. Here, the authors examine the role of invariant natural killer T (iNKT) and γδ-T cells in SpA and show that disease-derived iNKT and γδ-T cells have unique and Th17-skewed phenotype and gene expression profiles within inflamed joints.

    • Koen Venken
    • Peggy Jacques
    • Dirk Elewaut
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-15