The role that epistasis — non-additive interactions between alleles — plays in shaping population fitness is investigated in Drosophila melanogaster; the raw material to drive reproductive isolation is found to be segregating contemporaneously within species and does not necessarily require the emergence of incompatible mutations independently derived and fixed in allopatry.
- Russell B. Corbett-Detig
- Jun Zhou
- Julien F. Ayroles
