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Showing 1–4 of 4 results
Advanced filters: Author: Julien Mozziconacci Clear advanced filters

  • Inactivation of somatic SMC complexes in Caenorhabditis elegans shows that condensin I is the major long-range genome loop extruder, while cohesin forms small loops. Inactivation of cohesin, condensin II and condensin I/IDC causes minor transcriptional changes in autosomes.

    • Moushumi Das
    • Jennifer I. Semple
    • Peter Meister
    Research
    Nature Genetics
    Volume: 56, P: 1737-1749

  • ShRec3D (shortest-path reconstruction in 3D) converts sparse chromosome contact maps into spatial distances followed by 3D reconstruction.

    • Annick Lesne
    • Julien Riposo
    • Julien Mozziconacci
    Research
    Nature Methods
    Volume: 11, P: 1141-1143

  • Here, by sub-kb Hi-C and chromosome engineering, the authors visualize bacterial transcriptional units, showing that they form transcription-induced domains. Transcription-induced domains enforce constraints on nearby sequences, affecting their localization and dynamics.

    • Amaury Bignaud
    • Charlotte Cockram
    • Romain Koszul
    ResearchOpen Access
    Nature Structural & Molecular Biology
    Volume: 31, P: 489-497