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Showing 1–1 of 1 results
Advanced filters: Author: Julio J. Jiménez-Alonso Clear advanced filters
  • In this study, Green, Marttila, Kiweler et al. characterize one-carbon metabolism rewiring in response to a dual MTHFD1 and MTHFD2 inhibitor. This work provides insight into one-carbon fluxes, and reveals a previously uncharacterized vulnerability in cancer cells created by folate trapping.

    • Alanna C. Green
    • Petra Marttila
    • Johannes Meiser
    ResearchOpen Access
    Nature Metabolism
    Volume: 5, P: 642-659