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Advanced filters: Author: Jun-Song Wang Clear advanced filters

  • Redirection of the TCA cycle intermediate aconitate to itaconate production has anti-inflammatory effects. Here the authors show that the itaconate derivative 4-octyl-itaconate is anti-inflammatory partly as a result of inhibiting GAPDH enzymatic activity and thereby glycolysis in macrophages.

    • Shan-Ting Liao
    • Chao Han
    • Ling-Yi Kong
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11