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Showing 1–2 of 2 results
Advanced filters: Author: Jung-Lin Wu Clear advanced filters

  • B cell receptor (BCR) activation can trigger signalling causing apoptosis in order to eliminate auto-reactive B cells. Here the authors show that the O-GlcNAcylation and phosphorylation of lymphocyte-specific protein-1 are involved in a switch that regulates the initiation of apoptosis induced by BCR cross-linking.

    • Jung-Lin Wu
    • Hsin-Yi Wu
    • Kuo-I. Lin
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11

  • Post-translational modification has a variety of regulatory functions for important immune molecules. Here the authors use B-cell specific knockout mice to show how O-GlcNAcylation is required for functional B cell responses and humoral immunity.

    • Jung-Lin Wu
    • Ming-Feng Chiang
    • Kuo-I Lin
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-10