Nature Search

Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells

Junyu Wu
Chunyan Wu
Deyin Guo
Research22 Jun 2021
Cell Research

Volume: 31, P: 998-1010
Author Correction: Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells

Yuxi Chen
Jiaqi Liu
Zhou Songyang
Amendments and CorrectionsOpen Access09 Jul 2020
Nature Communications

Volume: 11, P: 1
SmedOB1 is Required for Planarian Homeostasis and Regeneration

Shanshan Yin
Yan Huang
Zhou Songyang
ResearchOpen Access22 Sept 2016
Scientific Reports

Volume: 6, P: 1-11
Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editors are an important contribution to the genome editing toolbox. Here the authors present EndoV-seq, an endonuclease-based assay for evaluating genomewide off-target effects of base editing.

Puping Liang
Xiaowei Xie
Zhou Songyang
ResearchOpen Access08 Jan 2019
Nature Communications

Volume: 10, P: 1-9
Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells

Class 1 type I CRISPR–Cas systems have not been as extensively developed for genome engineering as Class 2 systems. Here the authors modify the Type I–F CRISPR–Cas system for transcriptional activation of gene expression.

Yuxi Chen
Jiaqi Liu
Zhou Songyang
ResearchOpen Access19 Jun 2020
Nature Communications

Volume: 11, P: 1-14
Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX

Yang Hu
Guang Shi
Junjiu Huang
ResearchOpen Access31 Aug 2016
Scientific Reports

Volume: 6, P: 1-10
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

Here, iPS cell technology is used to study the mechanisms underlying dyskeratosis congenita in humans. Reprogramming restores telomere elongation in dyskeratosis congenita cells despite genetic lesions affecting telomerase. The reprogrammed cells were able to overcome a critical limitation in telomerase RNA component (TERC) levels to restore telomere maintenance and self-renewal, and multiple telomerase components are targeted by pluripotency-associated transcription factors.

Suneet Agarwal
Yuin-Han Loh
George Q. Daley
Research17 Feb 2010
Nature

Volume: 464, P: 292-296
Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility

Yuxi Chen
Puping Liang
Junjiu Huang
ResearchOpen Access22 Aug 2017
Cell Discovery

Volume: 3, P: 1-18
Efficient Production of Gene-Modified Mice using Staphylococcus aureus Cas9

Xiya Zhang
Puping Liang
Junjiu Huang
ResearchOpen Access02 Sept 2016
Scientific Reports

Volume: 6, P: 1-10
PDCL2 is essential for spermiogenesis and male fertility in mice

Minyan Li
Yuxi Chen
Xiya Zhang
ResearchOpen Access17 Oct 2022
Cell Death Discovery

Volume: 8, P: 1-9
USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy

Tao Liu
Liqiu Wang
Jun Cui
Research23 Oct 2020
Cellular & Molecular Immunology

Volume: 18, P: 2431-2442
Association of telomere length with authentic pluripotency of ES/iPS cells

Junjiu Huang
Fang Wang
Lin Liu
Research01 Feb 2011
Cell Research

Volume: 21, P: 779-792
m⁶A RNA modification controls autophagy through upregulating ULK1 protein abundance

Shouheng Jin
Xiya Zhang
Jun Cui
Correspondence25 Jul 2018
Cell Research

Volume: 28, P: 955-957

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Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells

Author Correction: Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells

SmedOB1 is Required for Planarian Homeostasis and Regeneration

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells

Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX

Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility

Efficient Production of Gene-Modified Mice using Staphylococcus aureus Cas9

PDCL2 is essential for spermiogenesis and male fertility in mice

USP19 suppresses inflammation and promotes M2-like macrophage polarization by manipulating NLRP3 function via autophagy

Association of telomere length with authentic pluripotency of ES/iPS cells

m⁶A RNA modification controls autophagy through upregulating ULK1 protein abundance

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