Nature Search

ACE2-dependent and -independent SARS-CoV-2 entries dictate viral replication and inflammatory response during infection

Duan et al. show that ACE2-dependent and ACE2-independent entry of SARS-COV-2 in epithelial cells versus myeloid cells differentially regulates viral replication and inflammatory responses, thereby contributing to COVID-19 progression and pathology.

Tianhao Duan
Changsheng Xing
Rong-Fu Wang
Research21 Mar 2024
Nature Cell Biology

Volume: 26, P: 628-644
Sharing without clicking on news in social media

Over 75% of links to news shared on Facebook during the election seasons of 2017–2020 were forwarded without the sharer first clicking on them. Extreme and user-aligned political content was shared more, aiding the spread of partisan misinformation.

S. Shyam Sundar
Eugene Cho Snyder
Guangqing Chi
Research19 Nov 2024
Nature Human Behaviour

Volume: 9, P: 156-168
Non-metallic iodine single-atom catalysts with optimized electronic structures for efficient Fenton-like reactions

Electronic structure modulation of active sites is important for Fenton-like catalysis. A non-metallic iodine single-atom catalyst with C-I coordination is reported here, which can effectively activate peroxymonosulfate into ¹O₂ for water treatment.

Junjun Pei
Jianbin Liu
Jinming Luo
ResearchOpen Access18 Jan 2025
Nature Communications

Volume: 16, P: 1-12
Structural insights into DNA N⁶-adenine methylation by the MTA1 complex

Junjun Yan
Feiqing Liu
Ping Yin
ResearchOpen Access20 Jan 2023
Cell Discovery

Volume: 9, P: 1-13
Micronuclear battery based on a coalescent energy transducer

A micronuclear battery is built based on an autoluminescent americium–terbium compound that couples radioisotopes with energy transducers at the molecular level, resulting in an 8,000-fold enhancement in energy conversion efficiency.

Kai Li
Congchong Yan
Shuao Wang
Research18 Sept 2024
Nature

Volume: 633, P: 811-815
Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition

Duozhi Chen
Jieyun Cai
Xiaojiang Hao
ResearchOpen Access07 Oct 2015
Scientific Reports

Volume: 5, P: 1-9
Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1

Most breast cancer patients are estrogen receptor positive and thus benefit from treatments that inhibit estrogen production; however, one third of tamoxifen-treated patients develops resistance and relapse. Here the authors show that tamoxifen resistant cells are resistant to chemotherapy because of BARD1 and BRCA1 upregulation.

Yinghua Zhu
Yujie Liu
Qiang Liu
ResearchOpen Access23 Apr 2018
Nature Communications

Volume: 9, P: 1-11
Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication

Pharmacological inhibitors of fatty acid synthase, including the approved anti-obesity drug orlistat, are shown to inhibit replication of SARS-CoV-2 in vitro and in a mouse model of infection in vivo.

Junjun Chu
Changsheng Xing
Rong-Fu Wang
Research27 Sept 2021
Nature Metabolism

Volume: 3, P: 1466-1475
A large-scale screen for coding variants predisposing to psoriasis

Xuejun Zhang, Jun Wang and colleagues report the application of exome sequencing to a large collection of psoriasis cases and controls. They identify seven common and low-frequency nonsynonymous variants within known psoriasis susceptibility genes that are associated with psoriasis risk.

Huayang Tang
Xin Jin
Xuejun Zhang
Research10 Nov 2013
Nature Genetics

Volume: 46, P: 45-50
COVID-19’s impact on visitation behavior to US national parks from communities of color: evidence from mobile phone data

Charles Alba
Bing Pan
Yun Liang
ResearchOpen Access04 Aug 2022
Scientific Reports

Volume: 12, P: 1-15
Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD

Hang Ma
Yingying Guo
Jianwei Zhu
ResearchOpen Access15 Feb 2022
Cell Discovery

Volume: 8, P: 1-14
USP7 deubiquitinates and stabilizes NOTCH1 in T-cell acute lymphoblastic leukemia

Huizhuang Shan
Xiangyun Li
Yingli Wu
ResearchOpen Access26 Oct 2018
Signal Transduction and Targeted Therapy

Volume: 3, P: 1-10
Analyses of soil microbial community compositions and functional genes reveal potential consequences of natural forest succession

Jing Cong
Yunfeng Yang
Yuguang Zhang
ResearchOpen Access06 May 2015
Scientific Reports

Volume: 5, P: 1-11
WTAP–VIRMA counteracts dsDNA binding of the m⁶A writer METTL3–METTL14 complex and maintains N⁶-adenosine methylation activity

Xuhui Yan
Feiqing Liu
Ping Yin
CorrespondenceOpen Access03 Oct 2023
Cell Discovery

Volume: 9, P: 1-5
AI-empowered integrative structural characterization of m⁶A methyltransferase complex

Xuhui Yan
Kai Pei
Ping Yin
CorrespondenceOpen Access10 Nov 2022
Cell Research

Volume: 32, P: 1124-1127

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