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Showing 1–7 of 7 results

Advanced filters: Author: Junlai Liu Clear advanced filters

mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity

Chronic alcohol use in humans and mice downregulates small intestinal mAChR4 and reduces goblet-cell-associated antigen passage formation, disrupting antimicrobial immunity.

Cristina Llorente
Fernanda Raya Tonetti
Bernd Schnabl
Research20 Aug 2025
Nature

Volume: 646, P: 180-189
Author Correction: Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome

Hua Su
Fei Yang
Michael Karin
Amendments and CorrectionsOpen Access18 Jun 2025
Nature

Volume: 643, P: E10
Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome

Cleaved and intact type I collagen have different effects on pancreatic ductal adenocarcinoma (PDAC), and remodelling of type I collagen—mediated through DDR1 signalling—is a prognostic indicator for the survival of patients with PDAC.

Hua Su
Fei Yang
Michael Karin
ResearchOpen Access05 Oct 2022
Nature

Volume: 610, P: 366-372
In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice

dCas9-mediated activation has been verified and widely used in vitro. Here the authors generated a potent in vivo activation platform and applied it to control the transcription of multiple genetic elements in the mammalian brain.

Haibo Zhou
Junlai Liu
Hui Yang
Research15 Jan 2018
Nature Neuroscience

Volume: 21, P: 440-446
Publisher Correction: Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome

Hua Su
Fei Yang
Michael Karin
Amendments and CorrectionsOpen Access07 Mar 2023
Nature

Volume: 615, P: E24
Impact of treatment modalities on prognosis of patients with metastatic renal collecting duct carcinoma

Xiaoyuan Qian
Junlai Wan
Ying Zhang
ResearchOpen Access25 Jul 2022
Scientific Reports

Volume: 12, P: 1-11
Homology-mediated end joining-based targeted integration using CRISPR/Cas9

Xuan Yao
Xing Wang
Hui Yang
ResearchOpen Access19 May 2017
Cell Research

Volume: 27, P: 801-814