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Showing 1–3 of 3 results
Advanced filters: Author: Justin A. Peruzzi Clear advanced filters

  • Understanding principles that govern protein association with extracellular vesicles should expand their potential as a therapeutic modality. Here, the authors show that by localizing proteins to the plasma membrane and lipid rafts, a variety of proteins can be preferentially loaded into extracellular vesicles.

    • Justin A. Peruzzi
    • Taylor F. Gunnels
    • Neha P. Kamat
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • The organization of membrane proteins is critical to cellular function. Here the authors explore how computational protein design, MD simulation, and cell-free systems can be combined to elucidate how membrane-protein hydrophobic mismatch affects protein folding and organization in synthetic lipid membranes.

    • Justin A. Peruzzi
    • Jan Steinkühler
    • Neha P. Kamat
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12