Nature Search

Translational framework linking perfluoroheptanoic acid (PFHpA) exposure to metabolic dysfunction associated steatotic liver disease in adolescents

Baumert, Maretti-Mira et al. integrate human epidemiological data and in vitro liver spheroid models to investigate PFHpA, an unregulated PFAS, in adolescent MASLD. Findings link PFHpA exposure to increased disease risk and identify key pathogenic mechanisms and potential therapeutic targets.

Brittney O. Baumert
Ana C. Maretti-Mira
Lida Chatzi
ResearchOpen Access29 Oct 2025
Communications Medicine

Volume: 5, P: 1-15
BMI metrics and their association with adiposity, cardiometabolic risk factors, and biomarkers in children and adolescents

Carolyn T. Bramante
Elise F. Palzer
Aaron S. Kelly
Research30 Oct 2021
International Journal of Obesity

Volume: 46, P: 359-365
Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes

The authors report PROTAC ternary complex structures involving the E3 ligase cIAP1 and target protein BTK, showing that cooperativity is not always correlated with degradation efficiency.

James Schiemer
Reto Horst
Matthew F. Calabrese
Research16 Nov 2020
Nature Chemical Biology

Volume: 17, P: 152-160
The current paradigm of bariatric surgery in adolescents

Severe obesity in adolescents affects their health and quality of life. Currently, metabolic and bariatric surgery (MBS) is the only effective intervention, but only a limited number of individuals undergo MBS procedures. Therefore, vigorous research in MBS is a priority for the benefit of adolescents with obesity.

Thomas H. Inge
Justin R. Ryder
Comments & Opinion29 Nov 2022
Nature Reviews Gastroenterology & Hepatology

Volume: 20, P: 1-2
Cathodoluminescence differentiates sedimentary organic matter types

Paul C. Hackley
Ryan J. McAleer
Justin E. Birdwell
ResearchOpen Access12 Mar 2024
Scientific Reports

Volume: 14, P: 1-10
Bone mineral density in young adults 5 to 11 years after adolescent metabolic and bariatric surgery for severe obesity compared to peers

Halley Wasserman
Todd Jenkins
Heidi J. Kalkwarf
Research04 Jan 2024
International Journal of Obesity

Volume: 48, P: 575-583
Direct evidence for shock-powered optical emission in a nova

Simultaneous optical and gamma-ray observations of nova V906 Carinae reveal correlated flares in both wavelength ranges that can be linked to shocks in the nova ejecta. Weak X-ray emission suggests that the shocks are deeply embedded, but they contribute substantially to the luminosity of the nova.

Elias Aydi
Kirill V . Sokolovsky
Jennifer L. Sokoloski
Research13 Apr 2020
Nature Astronomy

Volume: 4, P: 776-780
Impaired cardiac autonomic nervous system function is associated with pediatric hypertension independent of adiposity

Justin R. Ryder
Michael O'Connell
Aaron S. Kelly
Research21 Sept 2015
Pediatric Research

Volume: 79, P: 49-54
Prediction of adult class II/III obesity from childhood BMI: the i3C consortium

Jessica G. Woo
Nanhua Zhang
Alison Venn
Research09 Oct 2019
International Journal of Obesity

Volume: 44, P: 1164-1172
Association between endogenous sex hormones and adiposity in youth across a weight status spectrum

Subin Jang
Justin R. Ryder
Eric M. Bomberg
Research18 Sept 2024
Pediatric Research

Volume: 97, P: 1892-1899
Relation of secondhand smoke exposure to vascular phenotypes in children and adolescents

Michelle M. Harbin
Aaron S. Kelly
Justin R. Ryder
Research23 Oct 2019
Pediatric Research

Volume: 87, P: 760-766

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