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A multi-ancestry genetic reference for the Quebec population

In this article, the authors characterise genetic variation in CARTaGENE, a population-based cohort from Quebec, Canada. This genomic resource enables population and disease genetic studies in a founder population and other under-represented groups.

Peyton McClelland
Georgette Femerling
Guillaume Lettre
ResearchOpen Access03 Feb 2026
Nature Communications

Volume: 17, P: 1-17
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

A randomized trial in patients hospitalized with COVID-19 showed no benefit and potentially increased harm associated with the use of convalescent plasma, with subgroup analyses suggesting that the antibody profile in donor plasma is critical in determining clinical outcomes.

Philippe Bégin
Jeannie Callum
Donald M. Arnold
ResearchOpen Access09 Sept 2021
Nature Medicine

Volume: 27, P: 2012-2024
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption

When monkeys are infected with a virus similar to HIV, treated with antiretroviral therapy (ART), and are administered a ‘combo therapy’ made of antibodies against molecules that inhibit immune responses, they control viral rebound when ART is discontinued for more than 6 months

Susan Pereira Ribeiro
Zachary Strongin
Rafick P. Sekaly
ResearchOpen Access12 Sept 2024
Nature Immunology

Volume: 25, P: 1900-1912
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

The translation of many messenger RNAs that encode important oncogenes and transcription factors depends on the eIF4A RNA helicase to resolve G-quadruplex structures, implying eIF4A inhibition as an effective cancer therapy.

Andrew L. Wolfe
Kamini Singh
Hans-Guido Wendel
Research27 Jul 2014
Nature

Volume: 513, P: 65-70
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption

Susan Pereira Ribeiro
Zachary Strongin
Rafick P. Sekaly
Amendments and CorrectionsOpen Access16 Jan 2025
Nature Immunology

Volume: 26, P: 524
Increased Densities of Binding Sites for the Peripheral-Type Benzodiazepine Receptor Ligand [³H]PK 11195 in Congenital Ornithine Transcarbamylase-Deficient Sparse Fur Mouse

V L Raghavendra Rao
I A Qureshi
R F Butterworth
Research01 Dec 1993
Pediatric Research

Volume: 34, P: 777-780
Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response

Besma Benredjem
Jonathan Gallion
Graciela Pineyro
Amendments and CorrectionsOpen Access16 Apr 2020
Nature Communications

Volume: 11, P: 1
Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Amendments and CorrectionsOpen Access12 Jan 2022
Nature Medicine

Volume: 28, P: 212
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response

Identifying ligands which activate the specific effectors driving particular in vivo drug effects remains challenging. Here, the authors apply unsupervised clustering of pharmacodynamic parameters to classify GPCR ligands into different categories with similar signaling profiles and shared frequency of report of side effects.

Besma Benredjem
Jonathan Gallion
Graciela Pineyro
ResearchOpen Access09 Sept 2019
Nature Communications

Volume: 10, P: 1-15
711 SECRETORY DIARRHEA WITH PROTEIN-LOSING ENTEROPATHY, COLITIS CYSTICA SUPERFICIALIS AND CONGENITAL HEPATIC FIBROSIS: A NEW SYNDROME

Véronique A Pelletier
Narmer Galeano
Claude L Morin
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 229
Modeling human MLL-AF9 translocated acute myeloid leukemia from single donors reveals RET as a potential therapeutic target

F Barabé
L Gil
B T Wilhelm
Research26 Oct 2016
Leukemia

Volume: 31, P: 1166-1176
Exhausting repetitive piano tasks lead to local forearm manifestation of muscle fatigue and negatively affect musical parameters

Etienne Goubault
Felipe Verdugo
Fabien Dal Maso
ResearchOpen Access14 Apr 2021
Scientific Reports

Volume: 11, P: 1-14
PSYCHOLOGICAL ASSESSMENT OF PATIENTS WITH A DRAWING IN A PEDIATRIC HEMODIALYSIS UNIT

L Pelletier
F Sarrazin
R Langlois
Research01 Aug 1980
Pediatric Research

Volume: 14, P: 992
FOCAL GLOMERULAR SCLEROSIS IN CHILDHOOD: LONG TERM FOLLOW-UP

J G Mongeau
P Robitaille
M Pelletier
Research01 Aug 1980
Pediatric Research

Volume: 14, P: 1000
Neuromotor variability partially explains different endurance capacities of expert pianists

Etienne Goubault
Craig Turner
Felipe Verdugo
ResearchOpen Access13 Sept 2023
Scientific Reports

Volume: 13, P: 1-14
Prevention of bronchopulmonary dysplasia: a cross-sectional survey of clinical practices in Canada

Brooke Read
Guillaume Ethier
Amit Mukerji
Research23 Apr 2022
Journal of Perinatology

Volume: 42, P: 1255-1257

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