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Showing 1–3 of 3 results
Advanced filters: Author: Jyothy Raju Clear advanced filters

  • Allogeneic T cell therapies could be used in therapeutic applications because of their potential for ‘off-the-shelf’ access and standardised production. Here the authors have developed a multidimensional workflow profiling platform for EBV-specific T cell therapy and show that correlative biomarkers of T cell potency and effector function are associated with therapeutic effectiveness in xenogeneic mouse EBV-LCL models.

    • Corey Smith
    • Vijayendra Dasari
    • Rajiv Khanna
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-14

  • The T cell response to SARS-CoV-2 is important in protection from infection. Here the authors show by concentrating on a specific HLA haplotype that mutations in SARS-CoV-2 as new variants emerge can affect T cell recognition and reduce T cell responses to the virus.

    • Srividhya Swaminathan
    • Katie E. Lineburg
    • Corey Smith
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-6

  • Adoptive T-cell immunotherapy offers promise to patients who are resistant to standard anti-viral strategies. Here the authors describe clinical observations in patients with viral complications treated with adoptive immunotherapy over the last 15 years.

    • Michelle A. Neller
    • George R. Ambalathingal
    • Rajiv Khanna
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12