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Showing 1–2 of 2 results
Advanced filters: Author: Kaoru Iwano Clear advanced filters

  • DNA hypomethylating agents (HMAs) are used for the treatment of myeloid malignancies, but their therapeutic effects are not satisfactory. Here, the authors show that inhibition of TOPORS, which encodes a ubiquitin E3 ligase, augments the efficacy of HMAs through DNMT1 stabilization.

    • Satoshi Kaito
    • Kazumasa Aoyama
    • Atsushi Iwama
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • Initiations of magnetic reversals can be described by microstructures of the hot-deformed permanent magnet. Strong dipole fields are applied at magnetic-nucleation sites. Inclinations of easy axes from a nominal easy axis are essential to generate the magnetic nucleation. The magnetization reversal tends to starts from regions in which the grains having tilted easy axis are concentrated. The results of this study show that the performance of the hot-deformed permanent magnet is enhanced by avoiding the concentration of the grains with the tilted easy axis.

    • Hiroshi Tsukahara
    • Kaoru Iwano
    • Kanta Ono
    ResearchOpen Access
    NPG Asia Materials
    Volume: 12, P: 1-9