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Showing 1–2 of 2 results
Advanced filters: Author: Karoline K. Ebbesen Clear advanced filters

  • The circular RNA named ciRS-7 is overexpressed in human cancers, however, its spatial cellular expression patterns have not been explored. Here, the authors show that ciRS-7 is not expressed in colon cancer cells, but abundant in stromal cells within tumours, and that cancer-to-stromal cell ratios contribute to correlations between ciRS-7 and miR-7 target genes.

    • Lasse S. Kristensen
    • Karoline K. Ebbesen
    • Henrik Hager
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • In eukaryotes, circular RNAs (circRNAs) carry out important biological roles by acting as microRNA or protein sponges, regulating protein function or through cap-independent translation. New technologies for identifying and characterizing circRNAs will increase our knowledge of their biogenesis and function in health and disease.

    • Lasse S. Kristensen
    • Maria S. Andersen
    • Jørgen Kjems
    Reviews
    Nature Reviews Genetics
    Volume: 20, P: 675-691