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Showing 1–12 of 12 results
Advanced filters: Author: Karsten Kruse Clear advanced filters

  • Integer topological defects promote cellular self-organization, leading to the formation of complex cellular assemblies that trigger cell differentiation and the formation of swirling cellular pillars once differentiation is inhibited. These findings suggest that integer topological defects are important modulators of cellular differentiation and tissue morphogenesis.

    • Pau Guillamat
    • Carles Blanch-Mercader
    • Aurélien Roux
    Research
    Nature Materials
    Volume: 21, P: 588-597

  • Afonso et al. show that, during anaphase, chromosome movement can be driven by large cytoplasmic flows. These dynein-dependent cytoplasmic flows scale with cell size, slowing in smaller cells, thereby scaling anaphase.

    • Olga Afonso
    • Ludovic Dumoulin
    • Marcos Gonzalez-Gaitan
    ResearchOpen Access
    Nature Cell Biology
    Volume: 27, P: 273-282

  • The cytokinetic ring consists of actin and myosin, but their organisation prior to and during constriction has not been observed. Here the authors observe that mammalian and yeast cells organise their rings differently, with mammalian cells forming a periodic pattern of myosin clusters and yeast rotating myosin clusters during constriction.

    • Viktoria Wollrab
    • Raghavan Thiagarajan
    • Daniel Riveline
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-9

  • We classically consider the T cell compartment divided into cytotoxic CD8+ T cells and multiple, different helper CD4+ T cell subsets. Here the authors demonstrate that distinct memory CD8+ T cell subsets phenotypically inhabit CD4+ T cell like populations including some with helper-like characteristics.

    • Lucie Loyal
    • Sarah Warth
    • Andreas Thiel
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Spatial oscillation of the Min proteins directs septum formation during E. coli cell division. Using confocal and single molecule microscopy, the coordination of the membrane binding events that underlie this organization are now examined, giving insight into the dynamic events underlying this process.

    • Martin Loose
    • Elisabeth Fischer-Friedrich
    • Petra Schwille
    Research
    Nature Structural & Molecular Biology
    Volume: 18, P: 577-583

  • Active matter composed of filaments and molecular motors can contract. Here, the authors report the spontaneous out-of-plane buckling of reconstituted contracting poroelastic actomyosin sheets in the absence of external cues.

    • Y. Ideses
    • V. Erukhimovitch
    • A. Bernheim-Groswasser
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • Cytoplasmic flows are essential for various cellular processes. However, tools to manipulate these flows within cells are still lacking. Now research shows that an optical tool allows for control of cytoplasmic flows and can be used as a subcellular rheometer.

    • Karsten Kruse
    • Nicolas Chiaruttini
    • Aurélien Roux
    News & Views
    Nature Cell Biology
    Volume: 20, P: 227-228