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Advanced filters: Author: Kartoosh Heydari Clear advanced filters
  • Song et al. show that in young mice CD38 supports hematopoietic stem cell (HSC) proliferation by regulating Ca2+ signaling and mitochondrial activity. Conversely, the upregulation of CD38 during aging causes dysregulation of NAD metabolism, mitochondrial stress and HSC dysfunction.

    • Zehan Song
    • Sang Hee Park
    • Danica Chen
    Research
    Nature Aging
    Volume: 4, P: 1384-1393