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Author Correction: Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Elsa Bernard
Yasuhito Nannya
Elli Papaemmanuil
Amendments and Corrections04 May 2021
Nature Medicine

Volume: 27, P: 927
Author Correction: Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Elsa Bernard
Yasuhito Nannya
Elli Papaemmanuil
Amendments and Corrections09 Feb 2021
Nature Medicine

Volume: 27, P: 562
Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production

Double-stranded DNA (dsDNA) in the cytoplasm triggers IL-1β production as an antiviral response. Ruland and colleagues describe the formation of dsDNA-Rad50-CARD9 signaling complexes for NF-κB activation and the generation of pro-IL-1β after infection with a DNA virus.

Susanne Roth
Andrea Rottach
Jürgen Ruland
Research28 Apr 2014
Nature Immunology

Volume: 15, P: 538-545
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Clinical sequencing across a large prospective cohort of patients with myelodysplasic syndrome uncovers distinct associations between the mono- and biallelic states of TP53 and clinical presentation

Elsa Bernard
Yasuhito Nannya
Elli Papaemmanuil
Research03 Aug 2020
Nature Medicine

Volume: 26, P: 1549-1556
Immunogenic neoantigens derived from gene fusions stimulate T cell responses

Fusion proteins in cancers with low mutational burden represent functional neoantigens that elicit T cell activation and mediate responses to immunotherapy.

Wei Yang
Ken-Wing Lee
Luc G. T. Morris
Research22 Apr 2019
Nature Medicine

Volume: 25, P: 767-775