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Showing 1–7 of 7 results
Advanced filters: Author: Katharina Borst Clear advanced filters

  • In this atlas paper, the authors provide a transcriptomic and spatial taxonomy of myeloid cells in the central nervous system of mice and humans in health and pathology.

    • Chintan Chhatbar
    • Roman Sankowski
    • Marco Prinz
    ResearchOpen Access
    Nature Immunology
    Volume: 27, P: 1066-1080

  • Innate immune signaling pathways sense different microbial features and can elicit distinct yet overlapping immune responses. Here the authors dissect the contribution of these pathways to the response to MCMV infection and find that STING signaling is dispensable for host survival but crucial to restrict viral replication and dissemination via myeloid cells.

    • Pia-Katharina Tegtmeyer
    • Julia Spanier
    • Ulrich Kalinke
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-12

  • NAD serves as a 5′-terminal cap for bacterial and eukaryotic transcripts, and can be degraded at high temperatures to generate ADP-ribose (ADPR). Here, Gomes-Filho et al. identify NAD-RNAs in thermophilic and mesophilic archaea and provide insights into NAD- and ADPR-mediated turnover of RNAs in these organisms.

    • José Vicente Gomes-Filho
    • Ruth Breuer
    • Lennart Randau
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12

  • ACKR3 is a critical regulator of platelet-mediated thrombosis and organ injury following ischemia/reperfusion. Platelet ACKR3 surface expression is independently associated with all-cause mortality in patients with cardiovascular diseases.

    • Anne-Katrin Rohlfing
    • Kyra Kolb
    • Meinrad Gawaz
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-20

  • FlyWire presents a neuronal wiring diagram of the whole fly brain with annotations for cell types, classes, nerves, hemilineages and predicted neurotransmitters, with data products and an open ecosystem to facilitate exploration and browsing.

    • Sven Dorkenwald
    • Arie Matsliah
    • Meet Zandawala
    ResearchOpen Access
    Nature
    Volume: 634, P: 124-138

  • Primary lymphomas of the central nervous system (PCNSL) are defined as diffuse large B-cell lymphomas (DLBCL) confined to the CNS. Here, the authors complete whole genome sequencing and RNA-seq to characterize 51 PCNSLs, and find common mutations in immune pathways and upregulated TERT expression and find distinct pathway differences between DLBCL and other primary CNS lymphomas.

    • Josefine Radke
    • Naveed Ishaque
    • Frank L. Heppner
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-20