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Showing 1–3 of 3 results
Advanced filters: Author: Kathleen R. Stewart-Morgan Clear advanced filters

  • Stewart-Morgan et al. present isolation of DNA by 5-ethynyl-deoxyuridine labelling for mass spectrometry, a highly sensitive, quantitative mass spectrometry-based method for measuring DNA modifications on metabolically labelled DNA. They apply it to study DNA methylation and hydroxymethylation propagation.

    • Kathleen R. Stewart-Morgan
    • Cristina E. Requena
    • Anja Groth
    ResearchOpen Access
    Nature Cell Biology
    Volume: 25, P: 183-193

  • PWWP domains of DNMT3A and DNMT3B are proposed to interact with H3K36me3. Here the authors present a mouse model carrying a D329A point mutation in the DNMT3A PWWP domain and find this causes dominant postnatal growth retardation, with aberrant progressive gain of DNA methylation across domains marked by H3K27me3 in adult tissues.

    • Gintarė Sendžikaitė
    • Courtney W. Hanna
    • Gavin Kelsey
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-16

  • Groth and colleagues discuss recent advances in chromatin replication and maintenance across mitotic division, with emphasis on replication-coupled chromatin assembly and chromatin maturation post-replication.

    • Kathleen R. Stewart-Morgan
    • Nataliya Petryk
    • Anja Groth
    Reviews
    Nature Cell Biology
    Volume: 22, P: 361-371