Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–8 of 8 results
Advanced filters: Author: Katja Petzold Clear advanced filters

  • Biomolecules function through motion. Enabled by improved applicability of ¹H R1ρ NMR, we identify a hidden DNA intermediate and show how small molecules reshape its structural landscape, highlighting transient states as druggable targets.

    • Rubin Dasgupta
    • Christian Steinmetzger
    • Katja Petzold
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-13

  • Repression of a messenger RNA by a cognate microRNA depends not only on complementary base pairing, but also on the rearrangement of a single base pair, producing a conformation that fits better within the human Ago2 protein.

    • Lorenzo Baronti
    • Ileana Guzzetti
    • Katja Petzold
    Research
    Nature
    Volume: 583, P: 139-144

  • This study develops an NMR-based approach that can capture previously inaccessible, highly transient, low-populated ‘excited states’ in RNA; the localized rearrangements in base-pairing giving rise to these states are found to affect function by changing the exposure of residues required for a specific biological process.

    • Elizabeth A. Dethoff
    • Katja Petzold
    • Hashim M. Al-Hashimi
    Research
    Nature
    Volume: 491, P: 724-728

  • Mutating RNA one nucleotide at a time and measuring the impact of this on its chemical reactivity provides a strategy for determining its three-dimensional structure, and from there, hopefully, its function.

    • Katja Petzold
    • Hashim M. Al-Hashimi
    News & Views
    Nature Chemistry
    Volume: 3, P: 913-915

  • A subset of mitochondrial transcripts is not flanked by tRNAs and thus does not conform to the canonical mode of processing. Here, Clemente et al. demonstrate that phosphatase activity of ANGEL2 is required for correct processing of these transcripts.

    • Paula Clemente
    • Javier Calvo-Garrido
    • Anna Wredenberg
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • dG•dT and rG•rU ‘wobble’ mispairs in DNA and RNA transiently form base pairs with Watson–Crick geometry via tautomerization and ionization with probabilities that correlate with misincorporation probabilities during replication and translation.

    • Isaac J. Kimsey
    • Katja Petzold
    • Hashim M. Al-Hashimi
    Research
    Nature
    Volume: 519, P: 315-320