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Showing 1–2 of 2 results
Advanced filters: Author: Katja Selin Clear advanced filters
  • The colon is comprised of specialized cells that interact with each other to function, however, the molecular regionalization of the colon is incompletely understood. Here, the authors use spatial transcriptomics to generate a publicly available resource defining the transcriptomic regionalization of the colon during steady state and mucosal healing.

    • Sara M. Parigi
    • Ludvig Larsson
    • Eduardo J. Villablanca
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16
  • Attaining mucosal healing without immunosuppression is an attractive option for the treatment of inflammatory bowel disease (IBD). This Review describes the mechanisms of mucosal healing and how they might be altered in IBD and discusses potential therapeutic approaches to promote mucosal healing and regeneration.

    • Eduardo J. Villablanca
    • Katja Selin
    • Charlotte R. H. Hedin
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 19, P: 493-507