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Showing 1–4 of 4 results

Advanced filters: Author: Katrien Claes Clear advanced filters

OPENPichia: licence-free Komagataella phaffii chassis strains and toolkit for protein expression

Metabolic engineers and synthetic biologists can produce recombinant proteins at scale without royalty payments, or strain distribution constraints, using OPENPichia.

Katrien Claes
Dries Van Herpe
Nico Callewaert
ResearchOpen Access04 Mar 2024
Nature Microbiology

Volume: 9, P: 864-876
The Alzheimer’s therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia

Lecanemab, a leading therapy for Alzheimer’s disease, induces an Fc-mediated transcriptional program in human microglia, linked to osteopontin and enhanced plaque phagocytosis, suggesting alternative strategies to promote plaque clearance.

Giulia Albertini
Magdalena Zielonka
Bart De Strooper
ResearchOpen Access24 Nov 2025
Nature Neuroscience

Volume: 29, P: 100-110
Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition

Elizabeth E. Palmer
Michael Pusch
Vera M. Kalscheuer
ResearchOpen Access16 Nov 2022
Molecular Psychiatry

Volume: 28, P: 668-697
Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space

Adriaenssens et al. provide evidence suggesting that cytosolic small heat shock proteins localize to the mitochondrial intermembrane space, where they operate as molecular chaperones.

Elias Adriaenssens
Bob Asselbergh
Vincent Timmerman
ResearchOpen Access23 Jan 2023
Nature Cell Biology

Volume: 25, P: 467-480