Rtt109 is a relatively recently identified yeast histone acetyltransferase that forms distinct complexes with two histone chaperones. The structure of Rtt109 now reveals that while functionally distinct, it is structurally homologous to mammalian p300/CBP, which previously appeared to not contain a counterpart in yeast.
- Yong Tang
- Marc A Holbert
- Ronen Marmorstein
