Kidney injury disrupts the intricate renal architecture and triggers regeneration, inflammation and fibrosis. Here, Polonsky et al. used imaging based spatial transcriptomics (seqFISH) and identified distinct signaling between injured epithelial cells and fibroblasts and initiation of chronic immune responses to kidney injury.
- Michal Polonsky
- Louisa M. S. Gerhardt
- Andrew P. McMahon
