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Showing 1–3 of 3 results
Advanced filters: Author: Kaustav Sengupta Clear advanced filters

  • The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitating the discovery of potential effects of genetic variants, including variants associated with disease, on genome structure and function.

    • Job Dekker
    • Betul Akgol Oksuz
    • Feng Yue
    ResearchOpen Access
    Nature
    Volume: 649, P: 759-776

  • This Review discusses multiomic approaches for the characterization and biological understanding of cellular senescence, including detailed case studies on skeletal muscle and adipose tissue that highlight current outstanding issues in the field.

    • Sheng Li
    • Paula A. Agudelo Garcia
    • Rong Fan
    Reviews
    Nature Genetics
    Volume: 57, P: 2381-2394

  • This Perspective discusses strategies and challenges for the Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Consortium as it aims to catalogue the molecular and cellular phenotypes associated with null alleles of all human genes.

    • Mazhar Adli
    • Laralynne Przybyla
    • Justina Žurauskienė
    Reviews
    Nature
    Volume: 638, P: 351-359