8-oxoG is a common single-base DNA lesion caused by oxidative stress. Here, authors characterize the mutational signature of potassium bromate (KBrO3) exposure, the chromatin structural determinants of 8-oxoG-induced mutation and the mechanisms involved in the repair of KBrO3-induced 8-oxoG.
- Cameron Cordero
- Kavi P. M. Mehta
- Steven A. Roberts