Nature Search

Docetaxel-carboplatin as first line chemotherapy for epithelial ovarian cancer

P A Vasey
R Atkinson
S B Kaye
ResearchOpen Access16 Jan 2001
British Journal of Cancer

Volume: 84, P: 170-178
New discoveries of Australopithecus and Homo from Ledi-Geraru, Ethiopia

Hominin fossils from the Ledi-Geraru Research Project area, Ethiopia, suggest that early Homo and Australopithecus species co-existed in the region more than 2.5 million years ago.

Brian Villmoare
Lucas K. Delezene
Kaye E. Reed
ResearchOpen Access13 Aug 2025
Nature

P: 1-7
Induction of angiogenesis in a mouse model using engineered transcription factors

Edward J. Rebar
Yan Huang
Frank J. Giordano
Research04 Nov 2002
Nature Medicine

Volume: 8, P: 1427-1432
International Standard of Musical Pitch

G. W. C. KAYE
News05 Nov 1938
Nature

Volume: 142, P: 820-821
Epstein – Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-κB pathway involving TNF receptor-associated factors

Aristides G Eliopoulos
Maria Stack
Lawrence S Young
Research19 Jun 1997
Oncogene

Volume: 14, P: 2899-2916
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Leishmaniasis

Leishmaniasis is an endemic disease caused by Leishmania parasites and transmitted through the bite of female sandflies. In this Primer, Pareyn and colleagues review the epidemiology and pathophysiology of leishmaniasis, discuss current diagnosis and management, and identify future areas of research.

Myrthe Pareyn
Fabiana Alves
Johan van Griensven
Reviews20 Nov 2025
Nature Reviews Disease Primers

Volume: 11, P: 1-23
Bolus/infusional 5-fluorouracil and folinic acid for metastatic colorectal carcinoma: are suboptimal dosages being used in the UK?

DI Jodrell
LS Murray
J Cassidy
Research01 Oct 1994
British Journal of Cancer

Volume: 70, P: 749-752
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Late Pliocene environmental change during the transition from Australopithecus to Homo

Stable isotope and community faunal analysis of early hominid environments in the lower Awash Valley (Ethiopia) and Turkana Basin (Kenya/Ethiopia) reveal environmental change and divergence coincident with the emergence of the genus Homo (approx. 2.8 Ma).

Joshua R. Robinson
John Rowan
Kaye E. Reed
Research15 May 2017
Nature Ecology & Evolution

Volume: 1, P: 1-7
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
A new species of the mud terrapin Pelusios offers insights into early hominin habitats at the Pliocene Hadar Formation of Ethiopia

Brent Adrian
Christopher J. Campisano
Denise F. Su
ResearchOpen Access19 Nov 2025
Scientific Reports

Volume: 15, P: 1-18
Long-term biotic homogenization in the East African Rift System over the last 6 million years of hominin evolution

Spatial beta diversity analyses of mammalian fossil records from the East African Rift System reveal long-term biotic homogenization over the last six million years, a key time frame and context for human evolution.

John Rowan
Andrew Du
Jason M. Kamilar
Research15 Jul 2024
Nature Ecology & Evolution

Volume: 8, P: 1751-1759
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Characterization of a new Leishmania major strain for use in a controlled human infection model

Controlled human infection models (CHIMs) provide a pathway for accelerating vaccine development. Here, the authors describe the isolation, characterization, and GMP manufacture of a clinical Leishmania major strain to be used as a resource for CHIM studies of sand fly transmitted cutaneous leishmaniasis.

Helen Ashwin
Jovana Sadlova
Paul M. Kaye
ResearchOpen Access11 Jan 2021
Nature Communications

Volume: 12, P: 1-12
Hodgkin's disease mortality in Europe

C La Vecchia
F Levi
P Boyle
Research01 Oct 1991
British Journal of Cancer

Volume: 64, P: 723-734
Vulnerability of mineral-associated soil organic carbon to climate across global drylands

Protection afforded by inorganic minerals is assumed to make mineral-associated organic carbon less susceptible to loss under climate change than particulate organic carbon. However, a global study of soil organic carbon from drylands suggests that this is not the case.

Paloma Díaz-Martínez
Fernando T. Maestre
César Plaza
Research30 Jul 2024
Nature Climate Change

Volume: 14, P: 976-982
Hotspots of biogeochemical activity linked to aridity and plant traits across global drylands

In global drylands, soils tend to be more fertile beneath tree, shrub and grass islands. Soil fertility was greater beneath taller and wider plants but was unaffected by either grazing pressure or the type of herbivore.

David J. Eldridge
Jingyi Ding
Fernando T. Maestre
Research12 Apr 2024
Nature Plants

Volume: 10, P: 760-770
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Retinoids: present role and future potential

T R J Evans
S B Kaye
ResearchOpen Access26 Mar 1999
British Journal of Cancer

Volume: 80, P: 1-8
A map of human genome variation from population-scale sequencing

The goal of the 1000 Genomes Project is to provide in-depth information on variation in human genome sequences. In the pilot phase reported here, different strategies for genome-wide sequencing, using high-throughput sequencing platforms, were developed and compared. The resulting data set includes more than 95% of the currently accessible variants found in any individual, and can be used to inform association and functional studies.

Richard M. Durbin
David Altshuler (Co-Chair)
Gil A. McVean
ResearchOpen Access27 Oct 2010
Nature

Volume: 467, P: 1061-1073
A randomised study comparing standard dose carboplatin with chlorambucil and carboplatin in advanced ovarian cancer

EM Rankin
L Mill
RP Symonds
Research01 Feb 1992
British Journal of Cancer

Volume: 65, P: 275-281
A dose-finding study of carboplatin–epirubicin–docetaxel in advanced epithelial ovarian cancer

V J O'Neill
S B Kaye
P A Vasey
ResearchOpen Access07 May 2002
British Journal of Cancer

Volume: 86, P: 1385-1390
General relativistic orbital decay in a seven-minute-orbital-period eclipsing binary system

Observations of an eclipsing double-white-dwarf binary with an orbital period of 6.91 minutes that is decaying as predicted by general relativity are reported; once launched, the Laser Interferometer Space Antenna (LISA) should swiftly detect this binary.

Kevin B. Burdge
Michael W. Coughlin
Thomas A. Prince
Research24 Jul 2019
Nature

Volume: 571, P: 528-531
PEDIATRIC BURN VICTIMS: AN ECOBEHAVIORAL ANALYSIS

Kenneth J Tarnowski
L Kaye Rasnake
Thomas R Linscheid
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 185
Author Correction: Hotspots of biogeochemical activity linked to aridity and plant traits across global drylands

David J. Eldridge
Jingyi Ding
Fernando T. Maestre
Amendments and Corrections30 Apr 2024
Nature Plants

Volume: 10, P: 829
SCOTROC 2A: Carboplatin followed by docetaxel or docetaxel–gemcitabine as first-line chemotherapy for ovarian cancer

P A Vasey
R Atkinson
G J S Rustin
ResearchOpen Access11 Jan 2006
British Journal of Cancer

Volume: 94, P: 62-68
Development of a sensitive, quantitative assay with broad subtype specificity for detection of total HIV-1 nucleic acids in plasma and PBMC

C. N. Kibirige
M. Manak
J. Gilmour
ResearchOpen Access28 Jan 2022
Scientific Reports

Volume: 12, P: 1-16
Chinese scientists and US leadership in the life sciences

Steven H. Holtzman
Ron Cohen
Shuguang Zhang
Correspondence03 Oct 2019
Nature Biotechnology

Volume: 37, P: 1261-1263
Postpartum and Depression Status are Associated With Lower [¹¹C]raclopride BP_ND in Reproductive-Age Women

Eydie L Moses-Kolko
Julie C Price
Wayne C Drevets
Research18 Jan 2012
Neuropsychopharmacology

Volume: 37, P: 1422-1432

Search

Docetaxel-carboplatin as first line chemotherapy for epithelial ovarian cancer

New discoveries of Australopithecus and Homo from Ledi-Geraru, Ethiopia

Induction of angiogenesis in a mouse model using engineered transcription factors

International Standard of Musical Pitch

Epstein – Barr virus-encoded LMP1 and CD40 mediate IL-6 production in epithelial cells via an NF-κB pathway involving TNF receptor-associated factors

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Leishmaniasis

Bolus/infusional 5-fluorouracil and folinic acid for metastatic colorectal carcinoma: are suboptimal dosages being used in the UK?

Mapping the human genetic architecture of COVID-19

Late Pliocene environmental change during the transition from Australopithecus to Homo

Whole-genome sequencing reveals host factors underlying critical COVID-19

A second update on mapping the human genetic architecture of COVID-19

A new species of the mud terrapin Pelusios offers insights into early hominin habitats at the Pliocene Hadar Formation of Ethiopia

Long-term biotic homogenization in the East African Rift System over the last 6 million years of hominin evolution

Genetic mechanisms of critical illness in COVID-19

Characterization of a new Leishmania major strain for use in a controlled human infection model

Hodgkin's disease mortality in Europe

Vulnerability of mineral-associated soil organic carbon to climate across global drylands

Hotspots of biogeochemical activity linked to aridity and plant traits across global drylands

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Retinoids: present role and future potential

A map of human genome variation from population-scale sequencing

A randomised study comparing standard dose carboplatin with chlorambucil and carboplatin in advanced ovarian cancer

A dose-finding study of carboplatin–epirubicin–docetaxel in advanced epithelial ovarian cancer

General relativistic orbital decay in a seven-minute-orbital-period eclipsing binary system

PEDIATRIC BURN VICTIMS: AN ECOBEHAVIORAL ANALYSIS

Author Correction: Hotspots of biogeochemical activity linked to aridity and plant traits across global drylands

SCOTROC 2A: Carboplatin followed by docetaxel or docetaxel–gemcitabine as first-line chemotherapy for ovarian cancer

Development of a sensitive, quantitative assay with broad subtype specificity for detection of total HIV-1 nucleic acids in plasma and PBMC

Chinese scientists and US leadership in the life sciences

Postpartum and Depression Status are Associated With Lower [¹¹C]raclopride BP_ND in Reproductive-Age Women

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